0 projects

BIOBIOT-Biologi, bioteknologi, Mat. Nat.

Metal Ion Complexes of Nucleic Acid Constituents with Potentials in Antiviral and Anticancer Therapy

The research activity in biophysical/bioinorganic chemistry at Dept. of Chemistry, Univ. of Bergen involves several international projects, two of which within the framework of COST Action D20: Metal Jon Complexes of Nuceleic Acid Constituents with Potent ials in Antiviral and Anticancer Therapy....

Awarded: NOK 0.26 mill.

Project Period: 2002-2004

Location: Vestland

F-KJEM-Naturvitenskap, kjemi

Antibacterial fluoroquinolone drug binding to DNA mediated by metal ions

Over the last decade the fluoroquinolones have become a dominant class of antibacterial agents. How these drugs kill bacteria remains unclear. A large amount of biological data has indicated that the functional target for the drug action is the enzyme DNA gyrase, however, models involving direct ...

Awarded: NOK 1.3 mill.

Project Period: 2001-2005

Location: Vestland