0 projects

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KLINISK-Klinisk forskning

Arrangementstøtte for gjennomføring av "The first Joint World Congress of ISPGR and Gait & Mental Function", Trondheim 24.-28. juni 2012.

NTNU, Medisinsk fakultet står som arrangør av The first Joint World Congress of ISPGR and Gait & Mental Function i Trondheim 24.-28. juni 2012. Bevegelsesvansker som er hovedtemafor konferansen, er symptom på svært mange ulike sykdommer og tilstander. Årl ige kostnader ved slike funksjonsforstyrr...

Awarded: NOK 94,765

Project Period: 2012-2013

Location: Trøndelag - Trööndelage

BEHANDLING-God og treffsikker diagnostikk, behandling og rehabilitering

Metformin treatment of pregnant PCOS women and prevention of preterm birth.

Kvinner med polycystisk ovarie syndrom (PCOS) har vanskeligere for å bli gravide og har økt forekomst av svangerskaps-komplikasjoner som pre-eklampsi, svangerskapsdiabetes, fortidige fødsler og vekstretardasjon. Tidligere studier av gravide kvinner med PCOS har imidlertid hatt svakheter som gjør ...

Awarded: NOK 9.6 mill.

Project Period: 2012-2020

Location: Trøndelag - Trööndelage

FORINFRA-Nasj.sats. forskn.infrastrukt

Norwegian Brain Initiative (NORBRAIN): a large-scale infrastructure for 21st century neuroscience

The large-scale infrastructure initiative of the Research Council of Norway (RCN) is a one-time opportunity for rearmament of Norwegian neuroscience technology. The call provides an unprecedented opportunity for coordinated investment into high-cost state-of-the-art equipment needed to sample lar...

Awarded: NOK 80.0 mill.

Project Period: 2012-2016

Location: Trøndelag - Trööndelage

FRIMEDBIO-Fri prosj.st. med.,helse,biol

Transformation of grid signals to place signals in the mammalian space circuit

Det er kjent at posisjoneringssystemet i pattedyrhjernen inneholder flere funksjonelt spesialiserte celletyper, slik som plassceller i hippocampus og gitterceller, retningsceller og grenseceller i entorhinal cortex. Hvordan disse celletypene samhandler er imidlertid ikke godt forstått. Vi har tat...

Awarded: NOK 3.0 mill.

Project Period: 2012-2015

Location: Trøndelag - Trööndelage

HELSEVEL-Gode og effektive helse-, omsorgs- og velferdstjenester

Keeping patients out of hospital by improving patient trajectories in primary care - methodological development and effect

Bakgrunn for prosjektet er at data innsamlet i ulike register og journalsystem gir gode muligheter for å studere pasientforløp. Hvis disse kobles og knyttes til ulike mål på effekt og kvalitet blir det mulig å identifisere hvilke forløp som er mest fordelaktig både fra et pasient- og systemperspe...

Awarded: NOK 7.0 mill.

Project Period: 2012-2016

Location: Trøndelag - Trööndelage

HELSEVEL-Gode og effektive helse-, omsorgs- og velferdstjenester

The effects of DRG-based financing on hospital performance: productivity, quality and patient selection

En analyse av produktivitetsutviklingen i perioden 1999-2014 viser en samlet vekst pp omlag 25 % i denne 15-årsperioden. En stor del av denne veksten ser ut til å komme umiddelbart etter sykehusreformen i 2002, men det er også en svak vekst de siste 5-7 årene. Det har i denne perioden være en kra...

Awarded: NOK 9.4 mill.

Project Period: 2012-2017

Location: Trøndelag - Trööndelage

FRIMEDBIO-Fri prosj.st. med.,helse,biol

Mechanisms for vascular disease in women - Inflammation in pre-eclampsia and atherosclerosis

Kvinner med svangerskapsforgiftning (preeklampsi) har doblet risiko for hjerte- og karsykdom senere i livet. Svangerskapet er en metabolsk stresstest og unormale forandringer ved preeklampsi kan være et tidlig tegn på utvikling av hjerte- og karsykdom. Disse sykdommene er betennelses-sykdommer (i...

Awarded: NOK 5.1 mill.

Project Period: 2011-2017

Location: Trøndelag - Trööndelage

FRIMEDBIO-Fri prosj.st. med.,helse,biol

A spiking network model of neural pattern separation in the hippocampus

Can you remember your last birthday? -Then chances are you also remember where you were that day. Recent advances at the Center for the Biology of Memory (CBM) in Trondheim, Norway, have shed new light on why this is: a dedicated brain network continually keeps track of where we are -like a neur...

Awarded: NOK 1.6 mill.

Project Period: 2011-2014

Location: Trøndelag - Trööndelage

IS-NAD-Samarbeid med NORAD-land

Nilsen, Odd Georg. Norsk spesialist til Kina 2011

...

Awarded: NOK 10,000

Project Period: 2011-2011

Location: Trøndelag - Trööndelage

IS-TOPP-Toppfinans. av M.Curie-stipend

Elene Janberidze - European Intersectorial and Multi-disciplinary Palliative Care Research Training

EURO IMPACT aims to develop a multi-disciplinary, multi-professional and intersectorial educational and research training network aimed at monitoring and improving palliative care in Europe. Palliative care is less than optimal in many developed countries and some patients suffer from severe sym...

Awarded: NOK 0.47 mill.

Project Period: 2011-2017

Location: Trøndelag - Trööndelage

IS-TOPP-Toppfinans. av M.Curie-stipend

David Blum - European Intersectorial and Multi-disciplinary Palliative Care Research Training

Awarded: NOK 0.47 mill.

Project Period: 2011-2017

Location: Trøndelag - Trööndelage

FOLKEHELSE-Folkehelse

Gender Based Violence and childbirth - analyzing data from European cohort studies

Bakgrunn for studien Vold mot kvinner er et omfattende folkehelseproblem og et grovt menneskerettighetsbrudd som skjer verden over. De mest vanlige former for vold mot kvinner er fysisk, emosjonell og seksuell. Volden kan skje i alle alder og blir ofte delt inn i vold i barndommen og i voksen al...

Awarded: NOK 3.2 mill.

Project Period: 2011-2014

Location: Trøndelag - Trööndelage

FRIMEDBIO-Fri prosj.st. med.,helse,biol

Base excision repair proteins in DNA repair and early steps of adaptive immunity

DNA is continuously damaged by cellular and environmental agents. Five main DNA repair pathways correct such lesions. These are important in cancer prevention, but surprisingly, also for adaptive immunity. Our research group concentrates on base excision repair (BER) and direct repair of damage....

Awarded: NOK 5.3 mill.

Project Period: 2011-2014

Location: Trøndelag - Trööndelage

IS-BILAT-Mobilitet Norge-USA /Canada

Pharmacological fMRI and MRS of combined drug and cognitive behavioral training in children with moderate/severe traumatic brain injury.

Professor Robert F. Asarnow at UCLA has invited me to work in his lab for nine months collaboration on neuroimaging of pediatric TBI. UCLA is considered to be one of the most promising sites in the world when it comes to research on traumatic brain injur y, where most projects are a joint effort...

Awarded: NOK 0.14 mill.

Project Period: 2011-2011

Location: Trøndelag - Trööndelage

FRIMEDBIO-Fri prosj.st. med.,helse,biol

Biophysical properties underlying the representation of space in entorhinal cortex

In 2004-2005, behavioral unit recordings of rats exploring large open fields demonstrated that medial entorhinal cortex (mEC) 'grid cells' fire in spatially specific locations which repeat at regular intervals and form a hexagonal shape of firing activity and potentially provide the basic buildi...

Awarded: NOK 1.6 mill.

Project Period: 2011-2014

Location: Trøndelag - Trööndelage

BIOTEK2021-Bioteknologi for verdiskaping

Targeted screening technology for identification of bioactive agents with a potential for use in anti-cancer treatment from marine bacteria

I dette prosjektet har vi undersøkt ca 1000 ekstrakter fra en Actinomycete samling (bakterier) isolert fra Trondheimsfjorden med hensyn på anti-kreft aktivitet. Actinomyceter er bakteriene som er kjent å produsere mange ulike agens med anti-bakterie og anti-sopp egenskaper. Vi har undersøkt om de...

Awarded: NOK 3.0 mill.

Project Period: 2011-2014

Location: Trøndelag - Trööndelage

BEHANDLING-God og treffsikker diagnostikk, behandling og rehabilitering

Life After STroke - The LAST study

LAST studien er en nasjonal randomisert kontrollert multisenter studie som har til hensikt å undersøke effekten av et langtidsoppfølgingsprogram etter hjerneslag. Personer som har vært innlagt ved slagenheten ved St. Olavs Hospital eller ved Bærum sykehus får tilbud om å delta i studien ved den p...

Awarded: NOK 5.7 mill.

Project Period: 2011-2016

Location: Trøndelag - Trööndelage

FORINFRA-Nasj.sats. forskn.infrastrukt

A national infrastructure for biobanks and biobank related activity in Norway

There has been an accelerating interest by researchers world wide in gaining access to Norwegian biobanks with their comprehensive samples and data collections. In parallel, Norwegian researchers have gained increased competence and impact in this field, acknowledging the necessity to collabora...

Awarded: NOK 79.6 mill.

Project Period: 2011-2017

Location: Trøndelag - Trööndelage

GAVEFORST-Gaveforsterkningsordningen

Medisin, spatal orienteringsevne

...

Awarded: NOK 0.91 mill.

Project Period: 2011-2012

Location: Trøndelag - Trööndelage

FRIMEDBIO-Fri prosj.st. med.,helse,biol

Bio-Epidemiology of Fitness and Cardiovascular disease From Society to Molecules and back again

Awarded: NOK 9.4 mill.

Project Period: 2011-2015

Location: Trøndelag - Trööndelage

EVITA-eVitenskap

eGenVar - Handling, integrating, and analysing biobank data in a hypothesis-driven framework

Variants in DNA that affect gene expression - so-called regulatory variants - are thought to play important roles in common complex diseases, such as cancer. In contrast to variants in protein-coding regions, regulatory variants do not affect protein sequence and function. Instead, regulatory var...

Awarded: NOK 8.7 mill.

Project Period: 2011-2016

Location: Trøndelag - Trööndelage

UNIKARD-Nasjonal satsing hjerte- karfo

Bidrag til UNIKARD, Utgiftene til en kombinert koordinator- og seniorforskerstilling og driftsmidler til nettverksaktiviteter

UNIKARD - nasjonal satsning på hjerte- og karforskning UNIKARD er en nasjonal satsning på hjerte- og karforskning. UNIKARD omfatter all hjerte- og karforskning, men med hovedvekt på epidemiologisk forskning/registerforskning, hjertesvikt og hjerte- og karkirurgi. UNIKARD er en nasjonal for...

Awarded: NOK 8.0 mill.

Project Period: 2010-2015

Location: Trøndelag - Trööndelage

PETROMAKS-Maksimal utnyttelse av petroleumsreserver

Divers as Decompression Sickness Survivors: Exploring their Physical Exercise Involvement and Scheduling Efficacy

Physical activity in relation to the activity of diving, either before, during and after diving has been discussed widely the latest years. Traditionally, the common argument has been that divers in good, physical shape will have fewer decompression probl ems compared to divers in less good physi...

Awarded: NOK 1.6 mill.

Project Period: 2010-2012

Location: Trøndelag - Trööndelage

IS-BILAT-Mobilitet Norge-USA /Canada

Modeling neural mapping and remapping in the hippocampus

Navigation and memory for every-day episodes are thought to depend on the hippocampus and associated brain networks, supported by the characteristic properties of the underlying neural networks. Considerable progress in uncovering the neural basis for spa tial cognition in the hippocampus and par...

Awarded: NOK 0.23 mill.

Project Period: 2010-2011

Location: Trøndelag - Trööndelage

IS-BILAT-Mobilitet Norge-USA /Canada

Functions of the dentate gyrus

The hippocampus is known to play an important role in various types of memory both in humans and rodents. The dentate gyrus is a sub-region of the hippocampus and one of two places in the adult brain where new neurons are continuously added to existing ne tworks. The function of these adult born ...

Awarded: NOK 0.15 mill.

Project Period: 2010-2011

Location: Trøndelag - Trööndelage

FRIMEDBIO-Fri prosj.st. med.,helse,biol

Network functions of newly generated neurons and cellular mechanisms of place cell activity in adult hippocampus

In this proposed research program, we will combine state-of-art genetic and electrophysiological technologies to reveal mechanisms supporting adult hippocampus functions. The proposal is largely divided into two parts. 1) Network functions of newly gener ated neurons in adult dentate gyrus. New ...

Awarded: NOK 10.3 mill.

Project Period: 2010-2014

Location: Trøndelag - Trööndelage

RUSMIDDEL-Rusmiddelforskning

Problematic opioid use in the Norwegian general population and in HUNT 3: A register linkage and a prospective cohort study.

It is unknown as to how many people have problematic use of potentially addictive prescription drugs, which in Norway include opioids, benzodiazepines, and hypnotics. In the United States this is an invisible problem which is considered to be the second m ost widespread drug abuse, second only to...

Awarded: NOK 5.1 mill.

Project Period: 2010-2014

Location: Trøndelag - Trööndelage

FRIMEDBIO-Fri prosj.st. med.,helse,biol

Cellular Interactions with the Extracellular Matrix of Tumour Microenvironment

Interactions of cells (both tumour and stromal cells) with extracellular matrix (ECM) are an important part of the influence of the microenvironment on tumour progression. ECM interacts with cells via integrin receptors, as well as other receptors, and pr ovides signals for cell proliferation and...

Awarded: NOK 2.8 mill.

Project Period: 2010-2013

Location: Trøndelag - Trööndelage

FRIMEDBIO-Fri prosj.st. med.,helse,biol

Inflammasome activation by cholesterol crystals

Atherosclerotic lesions are focal thickenings of the innermost layer of the artery consisting of cells from the artery cell wall, connective tissue elements, liquid and crystalline lipids as well as blood-borne immune cells. Immune cells in atheroscleroti c lesions show signs of activation and pr...

Awarded: NOK 5.3 mill.

Project Period: 2010-2014

Location: Trøndelag - Trööndelage

FRIMEDBIO-Fri prosj.st. med.,helse,biol

The anatomy of memory: circuitry and functions of the hippocampal-parahippocampal region.

The human hippocampal-parahippocampal region plays an important role in memory. The relationship between the circuitry contained in this brain region and its contribution to memory is a topic of intense research, yet to date there is no complete and mecha nistic understanding of how the circuitry...

Awarded: NOK 3.0 mill.

Project Period: 2010-2014

Location: Trøndelag - Trööndelage

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