0 projects

IS-NABO-Nettverksprogram Norden-Næromr

Enn Seppet, EE14, Nabo 2006-07

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Awarded: NOK 0.19 mill.

Project Period: 2006-2007

Location: Ukjent Fylke

IS-NABO-Nettverksprogram Norden-Næromr

Tatjana Sjakste, LV11, Nabo 2006-07

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Awarded: NOK 0.18 mill.

Project Period: 2006-2007

Location: Ukjent Fylke

IS-STP-Statsstipendprogram, utlendinger

Balogh; J. Ungarn. STP 05/06

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Awarded: NOK 18,000

Project Period: 2006-2006

Location: Oslo

IS-STP-Statsstipendprogram, utlendinger

Czobel; S. Ungarn. STP 05/06

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Awarded: NOK 18,000

Project Period: 2006-2006

Location: Oslo

IS-STP-Statsstipendprogram, utlendinger

Peli Evelin R Ungarn STP 06/07

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Awarded: NOK 18,500

Project Period: 2006-2006

Location: Oslo

FRIBIO-Biologi og biomedisin

The study of translocation of extragenous growth factors into cells- mechanisms and biological function of intracellular growth factors.

The growth, development and repair of cells and organs are controlled by a variety of hormones, growth factors and cytokines. Many of these factors are proteins that bind to specific molecules (receptors) at the cell surface. These receptors reside in the plasma membrane. Lipid membranes control...

Awarded: NOK 3.1 mill.

Project Period: 2006-2011

Location: Oslo

FRIBIO-Biologi og biomedisin

Protein - DNA interactions at atomic levels

The project aims at exploring protein-DNA interactions at atomic levels using novel DNA-binding proteins. Protein targets will be selected from the genomes of the extremophiles Deinococcus radiodurans and Vibrio salmonicida and produced recombinant in qua ntities necessary for structural and func...

Awarded: NOK 3.1 mill.

Project Period: 2006-2011

Location: Troms - Romsa - Tromssa

FRIBIO-Biologi og biomedisin

Degradation of insoluble carbohydrate polymers: how do microbial chitinolytic machineries work?

Enzymatic degradation of abundant insoluble carbohydrate polymers such as cellulose and chitin is of tremendous biological and biotechnological importance. Microbes produce numerous enzymes to hydrolyze these polymers, but the question of how they manage to disrupt the crystalline structure of th...

Awarded: NOK 2.8 mill.

Project Period: 2006-2009

Location: Akershus

FRIBIO-Biologi og biomedisin

Effect of environmental DNA exposure on bacterial adaptation rates

The increasing amount of DNA sequence data available reveals that horizontal gene transfer (HGT) events have been frequent in most bacterial species. This observation identifies HGT as a major driving force in bacterial evolution. Whereas many studies hav e addressed the dynamics and mechanisms o...

Awarded: NOK 2.8 mill.

Project Period: 2006-2010

Location: Troms - Romsa - Tromssa

FRIBIO-Biologi og biomedisin

Hidden reservoirs of biological diversity - geobiology of unexplored endolithic communities associated with lichens

There is a large visible biological diversity on the surface of our planet, but it is less known that there are hidden reservoirs of biological diversity underneath the surface. Even if this subsurface biosphere is estimated to have a biomass of similar m agnitude as that of the surface biosphere...

Awarded: NOK 2.8 mill.

Project Period: 2006-2010

Location: Vestland

FRIBIO-Biologi og biomedisin

Activation of Toll-like receptors of the immune system studied by atomic force microscopy and confocal microscopy

Toll-like receptors (TLRs) trigger a fast response of the immune system to microbial particles that invade our body. TLRs recognize microbial conserved structures such as CpG-DNA or certain lipopolysaccharides, and are essential for our defense against mi crobes as well as for normal inflammatory...

Awarded: NOK 2.5 mill.

Project Period: 2006-2009

Location: Trøndelag - Trööndelage

FRIMEDBIO-Fri prosj.st. med.,helse,biol

Structural Glycobiology

The aim of the present research project is to structurally and functionally characterize the basis of protein carbohydrate recognition, with the long-term goal of engineering the carbohydrate specificity of carbohydrate binding proteins. This research fie ld is central to many cellular processes ...

Awarded: NOK 3.4 mill.

Project Period: 2006-2011

Location: Oslo

FRIBIO-Biologi og biomedisin

Developmental Biology of Dormancy Cycling

In perennial plants, like trees, the SAM is cycling between active and dormant states in synchrony with the season (Rinne et al. 2001; Rinne and van der Schoot 2003, 2004). The SD-induced development of dormancy and acclimation involves the obstruction of cellular contacts at the SAM, including ...

Awarded: NOK 2.4 mill.

Project Period: 2006-2009

Location: Akershus

FRIBIO-Biologi og biomedisin

The Biosynthesis of NAD in Humans: Isozymes and Subcellular Compartmentation

NAD is essential for energy transduction. It is also a key molecule in a variety of central signaling pathways. Nevertheless, surprisingly little is not known about its biosynthesis. Our recent research has established that NAD biosynthesis is absent from the cytosol: the three human isoforms of...

Awarded: NOK 3.1 mill.

Project Period: 2006-2009

Location: Vestland

BIA-Brukerstyrt innovasjonsarena

A novel antimicrobial agent for topical treatment of challenging infections caused by drug-resistant bacteria.

"Once life-saving medicines are increasingly having as little effect as a sugar pill. Since 1970, no new classes of antibacterials have been developed to combat infectious diseases. Microbial resistance to treatment could bring the world back to a pre-an tibiotic age." WHO Report 2000: Overcomi...

Awarded: NOK 8.8 mill.

Project Period: 2006-2009

Location: Oslo

IS-AUR-Samarb.progr. Norge Frankrike

Weltzien, Finn-Arne AUr06/07-36

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Awarded: NOK 36,315

Project Period: 2006-2008

Location: Oslo

IS-DAAD-Forskerutveksl. Norge-Tyskland

Iversen, Tor-Henning DAADppp-06 utsatt pga f. perm Vil rapportere i 07/08

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Awarded: NOK 18,000

Project Period: 2006-2007

Location: Trøndelag - Trööndelage

FRIBIO-Biologi og biomedisin

Hemoglobin polymorphism in Atlantic cod - finally unravelling the old puzzle

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Awarded: NOK 3.1 mill.

Project Period: 2006-2010

Location: Troms - Romsa - Tromssa

FRIBIO-Biologi og biomedisin

Biological Role of Regulatory Catalytic RNA in Eukaryotic Protein Gene Expression

A new main category of catalytic RNA (the GIR1 ribozyme) has been discovered and is under investigation in our laboratory. The group I-like ribozyme (GIR1; approx. 200 nt) is a unique example of a naturally occurring ribozyme with an evolved biological fu nction. GIR1 generates the 5'-end of a nu...

Awarded: NOK 2.8 mill.

Project Period: 2006-2011

Location: Troms - Romsa - Tromssa

FRIBIO-Biologi og biomedisin

Quorum sensing and transcriptional regulation in Gram-positive bacteria.

The bacteriocin production in Lactobacillus plantarum is regulated by the pln regulatory unit which is a quorum-sensing based signal transducing pathway. Such quorum-sensing based regulatory systems are of crucial importance in regulating gene expression in bacteria in response to environmental c...

Awarded: NOK 2.5 mill.

Project Period: 2006-2010

Location: Akershus

FRIBIO-Biologi og biomedisin

Functional Metagenomics to Study Prokaryotes from Arctic/ Sub-Arctic Springs of Hydrothermal Origin

The majority, in fact >99 % of the microorganisms on this planet have not yet been cultured in the laboratory and therefore have remained mostly uncharacterized and also unexploited for biotechnological purposes. Recent advancements in genomic technologie s, so called metagenomics, now allow to s...

Awarded: NOK 4.3 mill.

Project Period: 2006-2011

Location: Vestland

FRIMEDBIO-Fri prosj.st. med.,helse,biol

Cell cycle regulation: the role of replication clamps and interacting proteins

DNA replication is executed by enzymes called polymerases. The polymerases are tethered to the DNA template by binding to so-called clamps, which are doughtnut-shaped protein complexes encircling the DNA. The clamps are being loaded onto the DNA by clamp loaders, another protein complex. All orga...

Awarded: NOK 2.3 mill.

Project Period: 2006-2013

Location: Oslo

FRIBIO-Biologi og biomedisin

Features of developmental enhancers revealed by evolutionary processes in fish genomes: a computational and functional genomics approach

The loci of developmental transcriptional regulators are spanned by arrays of ultraconserved regulatory elements (UCRs), many of which exhibit high similarity across all vertebrates. This project aims to develop computational approaches for the generation of hypotheses about the function of thos...

Awarded: NOK 2.6 mill.

Project Period: 2006-2008

Location: Vestland

IS-BILAT-Mobilitet Norge-USA /Canada

Outbound mobility to City of Hope's Beckman Research Institute for two postdoctoral scholars who will do research on non-protein-coding RNA.

The proposal describes outbound mobility of two postdoctoral scholars and their families to City of Hope's Beckman Research Institute (Duarte, CA). The researchers are still partially employed by Interagon AS, where they have conducted their doctoral rese arch, but will now also be employed as po...

Awarded: NOK 0.23 mill.

Project Period: 2006-2007

Location: Østfold

IS-DAAD-Forskerutveksl. Norge-Tyskland

Birkeland, Nils-Kåre DAADppp-06

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Awarded: NOK 50,000

Project Period: 2006-2006

Location: Vestland

BIOMOL-Molekylær biovitenskap og bioteknologi

ESF Workshop/School: Microarray Gene Expression Analysis: Power and Potential of Standardisation

During the school, the participants will learn and discuss microarray gene expression analysis with an emphasis on standardisation and benchmarking. Curriculum includes central biological issues in transcript profiling, introduction to experimental design and data analysis, laboratory training i...

Awarded: NOK 59,999

Project Period: 2005-2006

Location: Trøndelag - Trööndelage

IS-BILAT-Mobilitet Norge-USA /Canada

Mechanisms of angiogenesis in the brain: Using retina as a model

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Awarded: NOK 0.16 mill.

Project Period: 2005-2007

Location: Oslo

IS-NAD-Samarbeid med NORAD-land

Sharma, Vijay K. indisk spes 2005

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Awarded: NOK 16,130

Project Period: 2005-2005

Location: Rogaland

PES-EU-Prosjektetablererstøtte EU (bedrift)

STREP - Improved, affordable and more precise tests for kidney function, especially in childhood

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Awarded: NOK 99,999

Project Period: 2005-2006

Location: Østfold

FRIBIO-Biologi og biomedisin

Functional sites in proteins: A combined proteomic and bioinformatical approach for improvement of a prediction system for linear motifs.

Functional sites in proteins are short stretches of amino acids that serve as binding sites, post-translational modification sites or proteolytic cleavage sites. Most functional features of proteins can be related to functional sites and/or globular domai ns. While there are several efficient met...

Awarded: NOK 3.1 mill.

Project Period: 2005-2009

Location: Vestland