Biomarkers for arrhythmia

Methanol leads to a large number of poisonings each year worldwide. Large outbreaks leads to significant deaths and inflict permanent brain damage and blindness. Patients are usually poisoned by drinking ethanol diluted with methanol. The toxicological principles of methanol are well known ; methanol is metabolized to formic acid, which in turn creates toxicity. Current treatment is effective if initiated early, but because of difficulties with diagnosis the morbidity and mortality remains high. Methanol analyzes are not widely available, and even in the western world, the delay from sampling to the result is often very long ( > 24-48 hours). In developing countries delay is much longer - if at all achievable. In addition, methanol poisoning mimic many medical conditions that make diagnosis difficult without proper analytical options. In this project we develop a fully disposable one-time use test strip for diagnosing methanol poisoning in humans. This tailored point-of- care product can be shipped anywhere in the world with small means, does not require laboratory equipment, nor laboratory personnel. It will have a global scope, and the first customers will be hospitals in selected endemic areas , outpatient clinics , and large international medical humanitarian organizations.

The aim of the current Project is to develop a Project concept and proposal for a Eurostars submission With deadline 02.03.2017 The specific topic is clinical Research and identification of potential blood Biomarkers for arrhythmia. The summary is of the Eurostars Project is provided in the attachement.