Research stay at Center for Clinical Metabolic Research

The Gut2Brain2020 project describes a Research stay at Center for Clinical Metabolic Research, Gentofte Hospital, Faculty of Health and Medical Sciences at University of Copenhagen. The host is Prof. Filip K. Knop who is Head of the Center. The applicant will also work together with Dr. Matt Gillum's research group at Novo Nordisk Foundation Center for Basic Metabolic Research. Both groups aim to identify and understand fundamental mechanisms and biological pathways underlying metabolic health and disease. This includes to identify metabolites generated through the gut microbiota, the gut and the liver and influencing the host's metabolism and appetite. Most of the research at these centers are done on mammals and an important aspect will be to summarize the state of the art in the research field and propose new cross-disciplinary ideas and directions for studies of metabolism, gastrointestinal physiology and the gut brain axis in fish, particularly in Atlantic salmon. Gut2Brain2020 promote competence-building in an important area for Norwegian aquaculture research and strengthen international collaboration with strong research groups in Denmark/EU, one of Norway’s priority partner countries by RCN. The planned research activities build on concepts regarding nutrient sensing and gut-brain signaling pathways that we have started to explore in RCN funded projects. The project will further expand the international and cross-disciplinary research collaboration on basic and applied research activities in the field. Activities include an extensive literature review and publishing papers. Based on this integration of new knowledge and together with the colleagues at CCMR the applicant will prepare project applications related to how individual feed components and feeding strategies affect appetite, growth, fat deposition and muscle formation. The overall aim is to benefit production of healthy and resilient fish.