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From the SEA to the SOLution. An integrative assessment of marine pollution in a changing Arctic

Marine chemical pollution poses known threats to human health and to biodiversity, ecosystem and societal services. The Arctic is a major sink of global mercury (Hg) pollution. Arctic sediments, sea and glacial ice constitute vast Hg reservoirs. Recent studies raise concerns about their increasing role as local Hg sources. In a rapidly warming Arctic, the consequences of potentially increased environmental Hg on marine biota remain unknown. The objective of SEASOL is to identify the pathway(s) of Hg bioaccumulation in marine food webs of the High Arctic Kongsfjorden (Svalbard). This changing glacial fjord is recognised as a ‘natural laboratory’ of climate change in the Arctic. The fellow’s earlier research has shown the sole measurement of Hg levels as insufficient to connect biotic Hg dynamics to environmental change, whereas the analysis of Hg stable isotopes proved to be a promising tool for source discrimination and biotic transfer. SEASOL will build on the novel application of stable isotope analysis to identify the sources of Hg within the fjord system and the pathways to Hg accumulation within sentinel marine species. On the short-term, the study will provide fundamental knowledge to help understand how emerging sources of Hg from rapid environmental change will impact Arctic marine predators. On the long-term, SEASOL will contribute to the development of early-warning, adaptive management strategies, including modelling, for mitigating the cumulative impact of pollutants and climate change on Arctic marine species. This multidisciplinary approach and the central position of the host institution (Norwegian Polar Institute) in the field of Polar Research will equip the Fellow with a broad set of new skills and lay the foundation for building her specific niche as a future leader in marine pollution science.

Optimization of Free Space Optical Communication Link based Drones for Search and Rescue Operations in the Arctic Region

The Arctic region is witnessing more frequent shipping accidents than ever which require accurate search and rescue operations. The existing communication systems use drones with radio frequency (RF) technology, which has limited bandwidth and cannot offer 4G/5G connectivity due to harsh weather constraints. It further limits the capacity of drones and affects the resolution of images and videos. The current research proposes to design free space optical communication (FSOC) link-based drones that can enhance connectivity between multiple drones and rescue ships as well as the capacity of drones to produce high resolution images and videos. The proposed FSOC-based drones can provide highspeed connectivity than the existing RF technology. The research will collect atmospheric turbulences data from the Arctic region and use it for designing the FSOC link. Furthermore, to enhance the capacity of FSOC-based drones, the research will design advanced multiplexing schemes (Mode Division Multiplexing and Orthogonal Code Division Multiple Access) and to ensure link stability, omnidirectional receiver will be designed. The research will further evaluate the performance of proposed FSOC link under the impact of various atmospheric turbulences. The expected outcomes of this research will lead to the optimisation of FSOC-based drones in expanding search areas and improving communication systems for SAR operations in the Arctic region.

AQUASERV – RESEARCH INFRASTRUCTURE SERVICES FOR SUSTAINABLE AQUACULTURE, FISHERIES AND THE BLUE ECONOMY

The overarching objectives of AQUASERV are to bring together, enhance, integrate and customise RI capacities (including facilities, instruments and expertise) and through the provision of transnational access (on-site or remote) and/or virtual access, to significantly further scientific advance and promote and facilitate the implementation of European Common Fisheries Policy, the Farm to Fork Strategy, the Sustainable Blue Economy and the European Green Deal.   AQUASERV will achieve these objectives by offering scientists from academia and business remote and on-site transnational (TA) and virtual (VA) access to an advanced set of European research infrastructures and its nodes related to research and management of marine and freshwater biological resources, food and biotechnology. These include the European Marine Biological Resource Centre ERIC (EMBRC), the Analysis and Experimentation on Ecosystems ERIC, The Aquaculture for Excellence for Aquaculture in Fish (Aquaexcel), and the Infrastructure for Promoting Metrology in Food and Nutrition (METROFOOD), as well as the International Council for Exploration of the Sea, both a service provider and stakeholder. It also includes the Research Infrastructure for Science and Innovation Policy Studies (RISIS) to bring contributions from the social sciences and to bring results nearer to policy makers ensuring societal impact.   To enhance, integrate and customise RI capacities, collaboration between partners and new pipelines to meet the objectives of the project will be developed during the first 3 years and will make available  to users.  To ensure these capacities will not be lost, a sustainability work package involving stakeholders will address the project legacy.    To maximize impact, AQUASERV will build a communication network among the partnership and develop a dissemination and outreach programme. Furthermore, an advanced training programme will be developed to capture future users and will be updated during the p

Aqua Research Infrastructure Services for the health and protection of our unique, oceans, seas and freshwater ecosystems

AQUARIUS will provide a highly comprehensive suite of integrated research infrastructures appropriate to addressing significant challenges for the long-term sustainability of our unique oceans, seas and freshwater ecosystems. For the first time, diverse research infrastructures will be combined to facilitate the work of researchers and key stakeholders focused on challenges and opportunities for both marine and freshwater systems. An impressive range of 57 research infrastructure services will be made available to include research vessels, mobile marine observation platforms, aircraft,  drones, satellite, sensors, fixed freshwater and marine observatories and test sites, experimental facilities, and sophisticated data infrastructures. AQUARIUS will support the development phase of the EU Mission to Restore our Ocean and waters by 2030, the Sustainable Blue Economy Partnership, the European Green Deal, and international climate initiatives. It will also be an essential component in achieving the European Digital Twin of the Ocean and the UN Decade for Ocean Sciences. The needs of researchers will be met through a robust and transparent system of transnational access funding Calls, facilitated by centralised user-friendly access portal. The Call programme will be informed through stakeholder engagement and brokerage events. Projects to be selected for Access must convincingly integrate multiple infrastructures and contribute to the core policy objectives of Mission Ocean, that is, to protect and restore marine and freshwater ecosystems and biodiversity; to prevent and eliminate pollution of our oceans, seas and waters; and to ensure a sustainable, carbon-neutral and circular blue economy. A thematic and geographic focus will be the hallmark of the proposed transnational Calls, aligning with the Lighthouse Regions, that is, the Baltic and the North Sea Basins, Black Sea, Atlantic/Arctic, and Mediterranean Sea along with their associated rivers.

Advance Marine Research Infrastructures Together

The European Ocean Observing System (EOOS) is the foundation of European ocean knowledge. The core Marine Research Infrastructures (MRIs) focused on ocean observing (EMSO, EURO-ARGO and ICOS ERICs; EuroFleets+, EuroGoShip, GROOM RI, JERICO RI and MINKE as INFRA projects) are the main providers of in situ ocean data for the EOOS and Copernicus, and the primary managers of instrumental capacity supporting fundamental research. These MRIs are aware that the lack of effective cross coordination prevents them from fully supporting frontier research, while the lack of integration makes it difficult to reach a critical mass for EOOS and results in significant cost duplication. Accordingly, AMRIT gathers these MRIs together with OceanOPS/WMO international coordination experience with the objective to: - ensure seamless operation of marine observation platforms ; - ensure the full nominal use of sensors and accelerate their evolution ; - exploit the complementarity of the various observation platforms ; - ensure the overall coherence of the ocean data value chain. To achieve these objectives, AMRIT will design and implement an EOOS Technical Support Center (EOOS TSC) for - a fully integrated information service across the data value chain from early planning stages to final delivery to users; - a cross-platform fully standardised data acquisition methodology for Essential Ocean Variables; - a collaborative federal structure to operate these services, relying on the ERIs and their members. The EOOS TSC will be the cornerstone in establishing and maintaining the EOOS, upon which European ocean observing can be strengthened in the coming decades. AMRIT will provide a catalyst for the development and consolidation of MRIs throughout Europe, providing a benchmark for operational coordination and collaboration. AMRIT will advance EOOS in line with its 2023-2027 Strategy and beyond, and the European Commission's ambitions for sharing responsibility in ocean observing across Europe.

Improve offshore infrastructure resilience against geohazards towards a changing climate

POSEIDON brings together an interdisciplinary and intersectoral team to deliver a professionally trained next-generation network of Doctoral Candidates to develop a step change in our capacity to identify, map, assess and predict offshore geohazards and in turn produce ground-breaking methods to prevent, mitigate and boost the resilience of current offshore infrastructure under a changing climate. The consortium is formed by experts across EU countries with universities, research institutions, industry partners and a government body to cover a full training programme on scientific and transferable skills.   The programme will undertake critical research across scales (from micro to macro) for seeking the inner links and differences, with an eventual aim to ascertain the pathways and grow our capacity for the enhancement of the existing and the robust development of new offshore infrastructure in the frame of safety and resiliency. In addition to the informed design and implementation of the novel physical/numerical modelling and lab studies, our approach is unique in the solid integration and utilisation of state-of-the-art data science technologies (e.g., data mining, machine learning, etc.) to their full potential. Only through this systematic approach, we can achieve the objectives of understanding the impact of offshore geohazards on our offshore critical infrastructures (OCIs) and developing novel models, tools and designs for future OCIs, such as, wind turbines, pipelines and cables.   The Doctoral Candidates will enjoy a highly integrated, interdisciplinary and intersector training environment, enriched through secondments with the network of non-academics. POSEIDON enables critical learning across all training aspects to ensure that comprehensive, robust and implementable solutions are obtained and validated to face the OCIs climate-resilient building.

POLARIN: POLAR RESEARCH INFRASTRUCTURE NETWORK

The polar regions play a key role in the Earth’s system. They are essential for our climate and are sentinels of climate change, human expansion, and the hunt of new resources. The polar regions are losing ice, and their oceans and land are changing rapidly. The consequences of this polar transition extend to the whole planet and are affecting people in multiple ways. Evidence-based policy recommendations are needed, but the polar regions are difficult to reach, and research infrastructures able to operate in these regions are scarce. To understand and predict key processes in the polar regions and provide evidence-based information, the polar research community needs access to world-class research infrastructure operating in these regions. POLARIN is an international network of polar research infrastructures and their services, aiming at addressing the scientific challenges of the polar regions. The network includes a wide array of complementary and interdisciplinary top level research infrastructures: Arctic and Antarctic research stations, research vessels and icebreakers operating at both poles, observatories, data infrastructures and ice and sediment core repositories. POLARIN will provide integrated, challenge-driven, and combined access to these infrastructures to facilitate interdisciplinary research on complex processes.  POLARIN will: 1.	Provide challenge-driven transnational access to a large portfolio of research infrastructures.  2.	Improve the access to data by improving data availability and interoperability between data infrastructures.  3.	Provide virtual access to data and data services.  4.	Provide data products for the scientific community and decision makers. 5.	Train the young generation of polar researchers in optimally exploiting the infrastructures for their research. 6.	Duly advertise the services offered by POLARIN and engage the infrastructure users to share their research outcomes with society. 

Material Science Innovation for Accelerated, Sustainable and Safe Implementation of Carbon Capture and Storage

MISSION-CCS presents a timely and unique doctoral network designed to deliver the next generation of highly trained researchers and entrepreneurs in the field of material science, specifically focused towards accelerating implementation of carbon capture and storage CCS technologies worldwide and ensuring the sustainable and safe operation of existing and future CCS systems.  The training network combines unique experimental system design and modelling approaches, state-of-the-art analytical technologies and techno-economic analysis to deliver a new generation of researchers and entrepreneurs. The programme of research training centres of delivering Doctoral Candidate Researchers (DCRs) with world-leading technical expertise in material science and engineering relevant to the entire CCS process. MISSION-CCS ensures that the subject-specific technical knowledge of each DCRs is under-pinned by inter-sectorial knowledge whilst also promoting wider innovation skills and relevant training on the techno-economics of CCS, developing experts with breadth of knowledge.  A central aim of the network is to forge a strong cohort culture, by ensuring that peer-to-peer learning and mutual support become the norm, in order to enhance experience. Research-led training activities are strengthened through a dynamic and interactive education based programme delivered by an internationally renowned consortium of academics and industrialists with complementary skills. As part of the training programme, subsequent to an introduction to CCS systems and the specific material science challenges, DCRs will gain knowledge of system design and optimisation, state-of-the-art analytical methods, theoretical modelling, techno-economics, and understand the challenges of exploiting their research. They will also acquire proficiency in project management, communication, entrepreneurship, and innovation; all essential attributes for any modern technical professional.

Land-Sea interface: Let’s observe together!

LandSeaLot will link together in situ, model and earth observations (EO) and connect related communities, citizens and initiatives such as Copernicus, ESA, EEA, GEOSS, EMODnet and the European Digital Twin of the Ocean. These observations will be used in a gap analysis to co-design a common land-sea interface observation strategy and an implementation plan. LandSeaLot participants will simultaneously work on improving: in situ and EO capabilities, models to reduce the model/observations gap and the integration of model, in situ and satellite data. Observation capacity will be increased through tested, improved and guided use of low-cost technology by citizens, facilitated by the network of European marinas. The technologies selected will be piloted in Integration Labs (ILs) together with improved and integrated in situ and EO observation techniques and model outputs. LandSeaLot ILs will cover selected areas in the Black, Aegean, Mediterranean, Atlantic, North and Baltic Seas, with a range of catchment, tidal and meteorological regimes. Experts and citizen science leaders will work in the ILs together with JERICO-RI, DANUBIUS-RI and ICOS-ERIC, and with regional policy makers and managers to tailor integrated observations that will provide them with information to manage societal challenges. These will include assessment of the lateral carbon flux and stock, plastics transfer, nutrients impact on primary production and eutrophication, supporting biodiversity conservation, improving modeling capability and supporting climate change adaptation (storm surge, floods, heat waves, coastal erosion, saltwater intrusion). Data generated in the ILs will be made FAIR available via EMODnet and interoperability, and semantic solutions for existing, international data flows will be developed. Relevant communities will be engaged by workshops, conferences, training, a high-tech summit and by a communication strategy including videos and policy briefs to ensure LandSeaLot’s legacy.

Optimisation of digital catch monitoring and reporting in European Fisheries

 OptiFish will strive to provide technological solutions that will simultaneously improve the sustainability of fisher’s operations, enhance control processes and strengthen society’s trust in their products. OptiFish will develop, test and recommend a set of innovative technologies and tools supported by artificial intelligence (AI) to provide the management, the fishing sector and the scientist with data on catch volumes, catch compositions and the fishing environment.  The goal is to unlock the full potential of technologies such as electronic and genetic monitoring for automated species recognition based on AI and computer vision to reduce discards, unreported landings and unreported fishing activities, ultimately establishing  a fisheries control and enforcement system fit for the digital age. The technologies are not enough alone, it is also critical to consider the combination of technologies and the integration of computer vision models, the wide range of data sources and their subsequent formats, while also addressing stakeholders needs and acceptance.  This goal cannot be achieved by a single project, which is why the aim of OptiFish is to lay a solid foundation for full technological development from which other projects and initiatives can be built. The project will place a strong focus on species recognition in different fisheries equipped with distinctly different catch handling facilities and in different European sea basins.  To ensure that these innovations are relevant to fisheries management, OptiFish has participation from the Norwegian Directorate of Fisheries, and has received written support from the European Fisheries Control Agency (EFCA), the Basque, Danish and Belgian Fisheries authorities.  

AleMo - Avanserte og bærekraftige aluminiumslegeringer for høytrykksstøpte komponenter til e-mobilitet

Midlene fra BIA-Brukerstyrt innovasjonsarena fordelt på år

Midlene fra BIA-Brukerstyrt innovasjonsarena fordelt på fylker

Midlene fra BIA-Brukerstyrt innovasjonsarena fordelt på fagområde

The overall target of the AleMo project is to develop high-pressure die cast aluminium alloys with improved properties and/or reduced CO2 footprint to increase the use of aluminium in electrically-powered vehicles. This will lead to lower emissions, longer driving ranges and reduced cost for new cars.
The automotive industry has ambitious plans to introduce large high-pressure die cast components in aluminium for new car models. One large high-pressure die cast aluminium component can replace many chassis parts, improving productivity and reducing cost.
These large components, in addition to new electrical components (e.g. battery boxes and electrical motor housings), result in a large demand for specially adapted aluminium alloys. Property requirements vary depending on the intended use and are different from requirements for more traditional parts in fossil cars. 
The project will therefore start by defining which alloying elements can lead to the desired properties by a thorough assessment of relevant elements. Construction of computer programs and simulation tools to quickly and efficiently predict the properties of the alloys will start imminently. Testing of promising alloys based on known alloying elements will be performed in a laboratory, and compared to results from simulations.
Additionally, possibilities to reduced the CO2 footprint of the alloys will be investigated by development and testing of more environmentally-friendly raw materials. Full scale testing of a new silicon master alloy will be performed in the project's first phase, and successful results will potentially lead to commercialization relatively early in the project period. 
Characterization of available scrap from the Norwegian/Nordic market will also be included in the first development phase to evaluate the potential for using post consumer scrap in the production of these alloys.

Reduced CO2 emissions and increased electrification are two of the most important trends in the automotive market. During the transition towards lower-emission vehicles, the average aluminium (Al) content in each vehicle is expected to increase significantly due continuous light-weighting and new emerging electrical components. Products based on high-pressure die casting (HPDC) of Al foundry alloys is believed to become particularly important.   
As one of the largest Al foundry alloy producers in Europe, Hydro Aluminium, together with Elkem (a world-leading Si producer), Stena (Norwegian subsidiary of Stena Recycling Group, the Nordic region's largest recycling company) and Nemak (a world-leading automotive component producer), in collaboration with R&D partners NTNU and SINTEF, has initiated this innovation project to meet the emerging demands from the automotive industry. 
The overall aim of the project is to develop HPDC Al alloys with superior properties and/or lower CO2 footprint for automotive light-weighting and electrification. Innovative alloys, which meet strict property requirements in the as-cast condition while maintaining sufficient castability for large volume production, will be developed. CO2 footprint reduction will be achieved by development of low CO2 Si raw materials, new alloying practices and reduced processing, in addition to introduction of post-consumed Al scrap based on innovative sorting and mapping methods.  A combination of computation modelling for property prediction and chemistry mapping, and laboratory-scale trials will be used to accelerate the development process. Promising alloy candidates will be tested in full-scale serial production, and the CO2 footprint of the alloys will be well documented. 
A successful innovation project will significantly improve the leading market positions and profitability of Hydro, Elkem and Stena in their corresponding business sectors, as well as significantly reduced production cost for Nemak.

AleMo - Advanced and Sustainable Aluminium Alloys for High-Pressure Die Cast Components for e-Mobility

Epitelial eggstokkreft har dårlig overlevelse. Det finnes ingen effektive strategier for tidlig oppdagelse, og tidlige sykdomssymptomer er ikke spesifikke for sykdommen (for eksempel oppblåsthet og hyppig vannlating). Den beste tilgjengelige blodbaserte biomarkøren for tidlig deteksjon for eggstokkreft er CA125, men denne markøren har begrenset evne til å skille mellom kvinner med sykdommen og de som er fri for kreft.
Denne studien vil gi den nødvendige valideringen av et panel av microRNA for EOC tidlig påvisning. Vi vil bruke serumprøver fra prospektive kohorter og kliniske studier. Målet er å validere et serologisk miRNA-panel som sammen med CA125 vil ha tilstrekkelig diagnostisk diskriminering til å bli brukt som et verktøy som sammen med  bildebehandling vil tillate tidlig diagnose og retning av pasienter med mistanke om malignitet til personlig spesialistbehandling.   Vi vil:
•	Validere serum miRNA-profiler som biomarkører for tidlig påvisning i prøver samlet inn fra tilfeller < = 3 år før EOC-diagnose og matchede kontroller, og karakterisere kilder til variasjon i miRNA-profiler.
•	Evaluer miRNA-profiler i klinisk setting og diskriminering mellom EOC-tilfeller og kvinner med (i) godartede ovarietumorer og (ii) underliggende komorbiditeter (inkludert andre krefttyper). Videre vil vi evaluere serum miRNA-profiler som prediktorer for tilbakefall og vil sammenligne tumorvev og serum miRNA-profiler.
•	Utvikle og optimalisere protokoller for dataintegrasjon og metoder for algoritmeutvikling.
•	Adressere etiske, juridiske og sosiale aspekter ("ELSA"), inkludert aktiviteter i viktige interessentgrupper. Utfordringer innen personvern og deling av helsedata, inkludert for utvikling av en kunstig intelligensmodell, vil  bli adressert, og det samme vil definisjonen av en "sunn" befolkning med hensyn til miRNA-profiler for EOC.

Epithelial ovarian cancer (EOC) is a lethal malignancy with poor survival. There are no effective early detection strategies, and early symptoms are vague. This study will provide validation of a miRNA panel for EOC early detection in serum samples from prospective cohorts, paired with clinical data and biospecimens. The project is organized as a consortium, where the collaborators are leading the Prospective Early Detection Consortium for Ovarian Cancer. We have used next generation sequencing to identify and validate a miRNA panel. The panel was developed and validated in patients with benign and malignant pelvic masses; and was further validated on a subset of patients and in silico. We have shown that the expression of circulating RNAs varies between healthy individuals and by age, sex, and lifestyle factors. Sources of variation in miRNA levels and the impact of confounders on discrimination between cases and non-cases must be evaluated. We plan to validate a serologic miRNA panel that, together with CA125, would have sufficient diagnostic discrimination for early-stage disease to be used clinically together with imaging, would allow early diagnosis and streaming of patients with suspected malignancy to personalized care. Toward that objective we will: -Validate serum miRNA profiles as biomarkers for EOC early detection in samples collected <=3 years before diagnosis and controls and characterize sources of variation in miRNA profiles. -Evaluate miRNA profiles in the clinical setting and the discrimination between EOC cases and (i) women with benign ovarian tumors in blood samples and (ii) women with underlying comorbidities. We will also evaluate miRNA profiles as predictors of recurrence and compare tumor tissue and serum miRNA profiles. -Develop and optimize protocols for data integration and methods for algorithm development and direct in silico validation. -Evaluate Ethical, Legal and Social Aspects (ELSA) of implementation in key stakeholder groups.

0 antall prosjekter

BEHANDLING-God og treffsikker diagnostikk, behandling og rehabilitering

miRNA as biomarkers in early detection and personalized treatment in ovarian cancer

Tildelt: kr 4,0 mill.

Prosjektperiode: 2023-2026

Sted: Oslo