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Reality-Connected Machine Simulation of Heavy Machinery

The RealSim project proposal aims to connect machine simulation to reality in the framework of heavy machinery, which is an interdisciplinary application. The results of this project are expected to optimize machine performance, accurately and reliably predict machine failure, and reduce overall development and operation costs, thus, serving the Europe’s priority of green transformation and the United Nation’s sustainable development goal 9. The RealSim project will close the gaps of: (1) Onboard estimations of force and pressure components of heavy machinery; (2) Estimating deformability, cylinder friction, leakage, and valve dynamics of heavy machinery using independent nonlinear Kalman filters; (3) Employing dependent nonlinear Kalman filters in state estimators of heavy machinery; (4) Tuning algorithms for the covariance matrix of plant noise in the state estimation of heavy machinery.   I will consolidate and leverage my research career and position as a leading researcher in the field through integration in Assoc. Prof. Mohammad Poursina’s group at the Department of Engineering Sciences of the University of Agder (UiA), Norway. Here, I will acquire hands-on experience of working with actual mechatronic systems and develop efficient control algorithms. I will improve my knowledge of fluid power designing, control theory, instrumentation, and develop efficient coding skills. I will also develop entrepreneurial skills. The skills, knowledge, and international network that I will develop during this fellowship will put me in an excellent position to achieve my long-term goal of becoming a professor with my own independent research group at an esteemed university in EU. This fellowship will help me to prepare a strong ERC Starting Grant application in the future. It will also cater my additional goal of setting-up a research-related start-up in the future.

Algebraic Theory of Information Quantities

Information theory is a discipline at the intersection of statistics, engineering and computer science. As the study of information quantities, such as compression or communication capacities, information content or measures of statistical dependency, it is one of the theoretical underpinnings of data science.  Computational problems in information theory are highly non-linear. The goal of this project is to transfer state-of-the-art methods of computational non-linear algebra to information theory, to study the inherent algebraic complexity of information-theoretical problems and to provide tools for solving them in practice. The algebraic point of view has proven to be fruitful in seemingly unrelated areas, as witnessed by a surge of recent work in algebraic statistics, in particular on likelihood geometry. However, maximizing the likelihood function is the same as minimizing relative entropy — a specific information quantity. Hence, this project also aims at generalizing the techniques developed in likelihood geometry.  One focus is on the practical computation of information quantities using numerical and differential algebraic geometry. Such quantities are defined via non-linear optimization problems and we aim to pinpoint the algebraic complexity of these problems in instances of general interest, such as common information measures. The final objective is finding fundamental laws and limits of data science imposed by non-linear inequalities constraining the entropic region. These inequalities provide, by duality, universal bounds for many of the optimization problems studied in information theory.

WHeelchair Activity Monitoring project (WHAM)

Wheelchair users (WCU) are three to five times more inactive than the general population, leading to a high risk of developing preventable secondary conditions. Although physical activity (PA) guidelines have been specifically developed for WCU, we lack systematic approaches to implement them in practice, as well as valid algorithms to monitor PA change in WCU through sensor-based solutions. Accordingly, the overall scientific aim of the WHeelchair Activity Monitoring project (WHAM) is to advance PA research and practice in WCU by developing valid digital markers for monitoring of and providing feedback on PA, paving the way for implementation and intervention. I will accomplish this through combining the complementary research fields of 1) behavioural intervention studies focusing on increasing PA in WCU (core competence University of British Columbia, UBC; outgoing phase) and 2) sensor-based PA monitoring (core competence Norwegian University of Science and Technology, NTNU; returning phase – consolidated by non-academic placement at Maastricht Instruments, which develop research prototypes including PA monitors). WHAM’s scientific aim is achieved through three objectives: 1) Measure the effect of a pragmatic exercise intervention trial on self-reported physical activity levels and cardio-respiratory fitness, 2) Develop valid algorithms for tracking PA markers in WCU, and 3) Co-create a framework that outlines how PA can be conjointly monitored and provided feedback on in WCU. This fellowship will enable me to become established as an internationally recognized researcher in the field of “physical activity and disability”, while bringing together ongoing national disjointed research activities in this field. Altogether, my overall ambition is to contribute to reducing inequalities in daily-life participation among WCU compared to the rest of the population.

EOSC Beyond: advancing innovation and collaboration for research

EOSC Beyond overall objective is to advance Open Science and innovation in research in the context of the European Open Science Cloud (EOSC) by providing new EOSC Core capabilities allowing scientific applications to find, compose and access multiple Open Science resources and offer them as integrated capabilities to researchers. To do so, EOSC Beyond supports a new concept of EOSC: a federated and integrated network of Nodes operated at different levels, national, regional, international and thematic, to serve the specific scientific missions of their stakeholders. Further specific objectives of the project are to accelerate ‘time to product’ of new scientific applications with software adapters, enable Open Science with machine composability and dynamic deployment of shared resources, support innovation in EOSC with a testing and integration environment, and align the EOSC Core architecture and specifications to integrate with European dataspaces. The project extends the state of the art of the EOSC Core and adopts a co-design methodology, including requirements elicitation, software development and validation in collaboration with different use cases from EOSC national and regional initiatives (e-Infra CZ, Czechia, NFDI, Germany, and NI4OS, South East Europe region), thematic research infrastructures from Social Sciences and Humanities (CESSDA), Life Sciences (CNB-CSIC and Instruct-ERIC), Environmental Science (ENES and LifeWatch), and Health and Food (METROFood-RI). EOSC Beyond builds on the capacities of prospective EOSC Nodes and partners with multi-annual experience in developing solutions for large-scale federated digital infrastructures and aligns with the technical architecture and requirements of data spaces from different business sectors. Ultimately, EOSC Beyond supports Open Science in modern, data-intensive, and multidisciplinary research, facilitating resource discovery, access, and reuse across scientific communities, organisations, and countries. 

Harmonization of Advanced Materials Ecosystems serving strategic Innovation Markets to pave the way to a Digital Materials & Product Passport

The overarching objective of DigiPass is to enhance the digital maturity of the European communities that develop materials and intermediate products. The project will develop recommendations and clear routes toward digitalized circular business models. The overarching key result of DigiPass is to create a sustainable platform which includes support for Digital Materials & Product Passport and for collaborative innovation-by-design processes in a circular economy served by advanced materials. A business model for operating such a platform completes the overarching objective. DigiPass is harmonizing and synergizing collected materials data sources and digital infrastructures. This will enable interoperability of data exchange, and standardization of advanced materials knowledge representation at all maturity levels. Accelerating the design, development, and production of advanced, safe, and sustainable chemicals and materials, as they are necessary for innovative products, calls for a collaborative approach involving different stakeholders to support durability, repair and overhaul, reuse, and recyclability of products. DigiPass project impacts all materials development communities over the whole circular value chain.  

Enhanced X(cross)-disciplinary Community-driven Imaging Technologies for Earth and Environmental material research

The EXCITE² Network is revolutionizing Earth and environmental material science research by consolidating a critical mass of 18 research facilities in 12 European and associated partner countries into a unified infrastructure and providing transnational access to advanced imaging technologies. This enables scientists to decipher complex processes within Earth materials at scales from nanometres to hundreds of centimetres, gaining unparalleled insight into the chemical and physical processes that govern, among others, environmental toxicity and its impact on human health, critical metal extraction for renewable energies, and the utilisation of Earth materials as long-term storage for climate-altering gases. The consortium fosters knowledge-sharing and talent attraction, bolstering the problem-solving capacity of the European Research Area. Moreover, EXCITE² is driving interdisciplinary collaboration and cross-fertilisation across academic institutions, scientific disciplines, and industry, propelling Europe towards a sustainable future. The initiative offers dedicated training programmes to a new generation of researchers within the European open science landscape, paired with access to world-class imaging facilities and expertise for problem-solving research and innovation. EXCITE² is introducing innovative service developments, such as artificial intelligence and leading-edge imaging experiments, to increase the user's problem-solving capacity. In addition, the consortium is implementing customised project valorisation strategies to maximize the impact of research outcomes in academia, society, and the economy. Citizen science projects allow the public to participate directly within the EXCITE² Network, contributing to solving EU challenges. As such, EXCITE² is paving the way towards a sustainable future, driving scientific excellence, and creating positive societal impact.

Engineering carbon quantum dots for zinc ion hybrid capacitors

Zinc ion hybrid capacitors (ZIHCs) integrate two energy storage mechanisms of battery-type electrode and capacitive electrode, bearing the advantages in energy density, power density, and safety. Until now, the cycle retention rate of ZIHC's capacity reported is still not more than 80%, restricting its development and commercial application severely. Focusing on the issue, the project aims at overcoming the limitation of traditional electrode materials and re-defining the designing concept to construct Carbon Quantum Dots (C-QDs) for ZIHCs. Advanced methods will be used to harvest carbon quantum dots from coal tar pitch (a sort of industrial solid castoff). The bulk sp2-carbon network, innumerable edge sites, profuse surface functional groups, and regular size ensures that as-synthesis C-QDs have high electrical conductivity, sufficient ion transport channels and rich adsorption sites. Moreover, the new concept of dynamic evolution is introduced for insight into the structure and interface failure of ZIHC's electrode. The interface-reconstruction mechanism and the attenuation model of capacity will be established for the first time. Further, the methods to strengthen structures of C-QD electrode will be developed based on a trade-off strategy. The ultimate goal is to improve the energy storage efficiency of ZIHCs by 20% and to increase their cycle performance more than 95% unprecedentedly. This research will develop long-running high performance ZIHCs, for contributing European energy storage industry. The ER will achieve abundant research experience and scientific skills from the project and the capability to launch her own research group in future.

Aqua Research Infrastructure Services for the health and protection of our unique, oceans, seas and freshwater ecosystems

AQUARIUS will provide a highly comprehensive suite of integrated research infrastructures appropriate to addressing significant challenges for the long-term sustainability of our unique oceans, seas and freshwater ecosystems. For the first time, diverse research infrastructures will be combined to facilitate the work of researchers and key stakeholders focused on challenges and opportunities for both marine and freshwater systems. An impressive range of 57 research infrastructure services will be made available to include research vessels, mobile marine observation platforms, aircraft,  drones, satellite, sensors, fixed freshwater and marine observatories and test sites, experimental facilities, and sophisticated data infrastructures. AQUARIUS will support the development phase of the EU Mission to Restore our Ocean and waters by 2030, the Sustainable Blue Economy Partnership, the European Green Deal, and international climate initiatives. It will also be an essential component in achieving the European Digital Twin of the Ocean and the UN Decade for Ocean Sciences. The needs of researchers will be met through a robust and transparent system of transnational access funding Calls, facilitated by centralised user-friendly access portal. The Call programme will be informed through stakeholder engagement and brokerage events. Projects to be selected for Access must convincingly integrate multiple infrastructures and contribute to the core policy objectives of Mission Ocean, that is, to protect and restore marine and freshwater ecosystems and biodiversity; to prevent and eliminate pollution of our oceans, seas and waters; and to ensure a sustainable, carbon-neutral and circular blue economy. A thematic and geographic focus will be the hallmark of the proposed transnational Calls, aligning with the Lighthouse Regions, that is, the Baltic and the North Sea Basins, Black Sea, Atlantic/Arctic, and Mediterranean Sea along with their associated rivers.

EOSC-ENTRUST: A European Network of TRUSTed research environments

The mission of EOSC-ENTRUST is to create a European network of trusted research environments for sensitive data and to drive European interoperability by joint development of a common blueprint for federated data access and analysis.  Countries and institutions have made significant investments in secure and trusted data environments to meet the need for research and policy-driven analysis of sensitive datasets such as people's health and socio-economic status, the habitats of vulnerable species and geo-spatial locations of protected sites. There are now a large number of such secure environments in operation - linked to national centres, individual organisations or specific research communities. This fragmented landscape poses challenges for both users and providers: researchers are faced with a large number of different systems and access procedures; providers need to manage federated access across multiple, potentially incompatible, technology and governance frameworks. EOSC-ENTRUST brings together providers of operational Trusted Research Environments from 15 European countries with a shared goal to implement, validate and promote their capabilities through a common European framework using shared standards and common legal, operational and technical language. This blueprint for interoperability is anchored in the EOSC Interoperability Framework spanning the four dimensions of Legal, Organisational, Technical and Semantic interoperability. EOSC-ENTRUST has identified four driver projects covering Genomics, Clinical trials, Social science, and public-private partnerships to benchmark capabilities, inform blueprint design and demonstrate secure  data analysis using federated workflows. Targeted outreach activities will expand this open network with further providers and develop policy papers and guidelines for the full range of stakeholders to create a long-term operational TRE framework within the European Open Science Cloud. 

IMProving User experience, Long-term sustainability and Services of EU-OPENSCREEN

EU-OPENSCREEN (EU-OS), the distributed European Research Infrastructure for Chemical Biology and early drug discovery, provides world-class services in high-throughput compound screening and medicinal chemistry to users from academia and industry. As one of the largest open-access initiative globally, EU-OPENSCREEN plays an increasingly important role in facilitating early stage drug discovery in Europe. It recently integrated fragment-based drug discovery and chemoproteomics as two new services, but the increasing complexity of modern drug discovery projects requires an even more comprehensive portfolio and integration of emerging technologies. To ensure that EU-OS continues to offer a comprehensive suite of relevant services and support a growing user community to conduct forefront research, IMPULSE will develop, validate and integrate new services in AI/ML, new chemical modalities, and innovative disease-relevant cell models combined with CRISPR-Cas9/RNAi-based genetic screening. IMPULSE will work towards the implementation of common operational and data standards to increase data reproducibility and FAIRness. Bespoke outreach and training activities will raise awareness among key user groups of its new services and advance operational excellence and reproducibility in pre-clinical drug discovery. New models for pre-competitive drug discovery with industry or charities, and growing ERIC member community will reinforce the sustainability and accessibility of EU-OPENSCREEN.

Autonome langdistanse underisoppdrag for karakterisering av lys og vannsøylen

Midlene fra SSF-Svalbard Science Forum fordelt på år

Midlene fra SSF-Svalbard Science Forum fordelt på fylker

Midlene fra SSF-Svalbard Science Forum fordelt på fagområde

Senior Researcher

Arctic Under-Ice Exploration with Autonomous Gliders
An international team aims to revolutionize studying remote Arctic under-ice environments using autonomous underwater vehicles called hybrid gliders. As sea ice diminishes due to climate change, the ecosystems below face new challenges and opportunities for research.
This diverse team, including engineers, marine biologists, optical scientists, and Arctic researchers from Norway, the US, and UK, brings crucial expertise to tackle the complexities of Arctic research.
Hybrid Glider Technology
These hybrid gliders can traverse vast distances beneath the ice with advanced sensors adapted for harsh polar conditions. Operating autonomously allows gathering critical data without the environmental impact of traditional ship-based research.
The primary goal is establishing an international network harnessing these gliders to investigate under-ice light conditions and ecological impacts. This network aims to enhance scientific understanding while pioneering environmentally-friendly technologies.
Mapping Light Dynamics and Demonstrating Potential
Mapping under-ice light dynamics will inform climate models. The project also demonstrates gliders' potential to reduce the need for larger, costlier research vessels, elevating Svalbard's status as an Arctic research hub.
However, deploying gliders presents challenges like sensor optimization, autonomy, and data management. The collected data will provide insights for policymakers on Arctic conservation strategies.
Environmentally Conscious Arctic Research
By embracing innovative autonomous technologies, this project expands our under-ice ecosystem understanding while inspiring environmentally-conscious research methods. The insights could shape future approaches to studying and preserving this vulnerable region, setting new standards for ecological studies in extreme environments.

The Arctic Ocean is changing rapidly, and the areas beneath the sea ice are among the least understood on the planet. This project aims to transform our ability to study this environment by developing a new research network that will use cutting-edge autonomous underwater vehicles called hybrid gliders. These gliders can travel for long distances and operate safely near the underside of ice, offering an unprecedented opportunity to gather data on light conditions and their ecological impacts beneath the ice.

Objectives

-Create a lasting international research network focused on using hybrid gliders to study under-ice ecosystems, particularly around Svalbard.
-Demonstrate hybrid glider technology 'in the field', helping scientists understand its capabilities and informing engineers of scientists' research needs.
-Seek major funding to launch a comprehensive Arctic research program using hybrid gliders to collect critical data that's currently challenging and risky to obtain.

Critical R&D Challenges
-Adapting sensors: Existing sensors designed for measuring light and ocean conditions need to be optimized for use on long-duration, under-ice missions.
-Improving glider autonomy: Ensuring the gliders can navigate safely under the ice, make intelligent decisions, and reliably return to the surface for data transmission in a dynamic environment.
-Data handling: Developing effective systems to process and interpret the large amounts of data collected during long-range missions.

Interdisciplinary Approach: This project unites engineers, Arctic marine experts, optical scientists, and researchers from Norway, the US, UK, and beyond, creating a unique and powerful problem-solving team.

Autonomous long-range under-ice missions for light and water column characterisation

Understanding genetic architecture, the underlying basis of phenotypic traits, and its relationship to evolutionary change, is a major challenge for evolutionary biologists. Variation in gene expression is one of the most important factors causing phenoty pic variation. We will study the role of the Y chromosome of Drosophila melanogaster in regulation of gene expression on the X chromosome and the autosomes. Widespread regulatory effects of the Y chromosome was discovered in a study published in Science i n 2008 by the Hartl laboratory at Harvard University using Y chromosomes from different populations in the same genetic background and measuring the difference in gene expression. The discovery of Y-linked regulatory variation (YRV) on a genome-wide scale  is a new phenomenon that motivates studies of its mechanisms, adaptive significance, and evolutionary dynamics. Our hypothesis is that the polymorphic Y chromosome differs in the number of binding sites that compete with YRV-responsive genes for chromati n-associated proteins that are present in limited amounts in the cells. These binding sites are most likely repetitive sequences that make up the majority of the heterochromatic Y chromosome. We aim to: A) Identify which region(s) on the Y that participat es in the regulation of genes on the X chromosome and the autosomes; B)  Develop markers to measure differences in repetitive sequences on the Y; C) Test the involvement of known regulatory pathways in YRV, especially the pathway mediated by suppressors o f PEV (position effect variegation) and that mediated by repeat-associated small inhibitory RNA (rasiRNA); D) Determine which genes are differentially affected by polymorphic Y present in XXY females. Arguing in favor of our hypothesis is the known high d egree of polymorphism in rDNA and Su(Ste) repeats, the effect of the Y chromosome in modulating PEV, and the specificity of binding of key chromatin-associated proteins with microsat sequences on the Y.

Genetic architecture in Drosophila - The role of the Y chromosome in gene expression across the genome.

In this project Drosophila genetics will be used to test the hypothesis that the Y chromosome effects on gene expression result from blocks of simple-sequence DNA in the Y chromosome that compete for DNA-binding proteins that affect gene expression.

The  aims and challenges of this work are:

1. To identify which regions of the Y chromosome regulate genes whose expression is modulated by Y-linked regulatory variation (YRV). We will use deletion-mapping experiments by utilizing X-Y translocations based on  the previous successful work by Dr. Ping Zhang; subsequent microarray hybridizations will correlate these results with changes in gene expression. For any identified regions that contain a known fertility factor, we will test their effects by examining mu tants, either P-element knockouts or known deletions.

2. Test genes in candidate pathways that could possibly be involved in mediating the Y-chromosome effects on gene regulation. There are two sets of well-characterized genes available which are involve d in two candidate pathways: position effect variegation (PEV) and repeat-associated small interfering RNA (rasiRNA), respectively. Mutant alleles in these pathways will be tested for their interaction with YRV. 

The long-term goal of the research is to  gain a better understanding of how the regulatory role of the Y chromosome contributes to genetic variation and evolution. Understanding the mechanism and adaptive significance of YRV will likely transform the current paradigm that assigns only a minor ro le to the Y chromosome in promoting adaptive phenotypic evolution. These results also raise the question of how widespread Y-linked regulatory variation may be in other organisms with similarly heterochromatin-rich Y chromosomes, including humans and othe r mammals. Our results may also help explain why approximately two percent of human males are infertile because of defects in sperm production.

0 antall prosjekter

FRIMEDBIO-Fri prosj.st. med.,helse,biol

Genetic architecture in Drosophila - The role of the Y chromosome in gene expression across the genome.

Tildelt: kr 3,2 mill.

Prosjektperiode: 2011-2014

Sted: Oslo

IS-BILAT-Mobilitet Norge-USA /Canada

Molecular mechanisms of gene regulation in autosomal and X-linked genes by the Y chromosome in Drosophila.

Tildelt: kr 0,15 mill.

Prosjektperiode: 2010-2011

Sted: Oslo