0 antall prosjekter

FRIMED-Klinisk medisin og folkehelse

Pathophysiological and Immunological Aspects of Meconium Aspiration Syndrom A search for new understanding and therapy

Meconiumstained amniotic fluid is present in approximately 10-12% of all deliveries. Out of these approximately 5% develop respiratory problems called Meconium Aspiration Syndrom (MAS). This is caused by aspiration of fetal stools (meconium into the lungs ) and occur mainly in term or postterm in...

Tildelt: kr 1,8 mill.

Prosjektperiode: 2005-2008

Sted: Oslo

AKLIMED-Klinisk medisin

Development of methodology and equipment for assessing postural stability during standing and walking

Finegrained methods are needed to assess postural stability during standing and walking. Such measures must be reliable, valid and easy to use under real life conditions. The Balance and Gait Unit, University of Bergen is a member of the EC thematic netwo rk Prevention of Falls Network Europe (PR...

Tildelt: kr 0,40 mill.

Prosjektperiode: 2005-2006

Sted: Vestland

FRIMED-Klinisk medisin og folkehelse

Induced Liver Hyperplasia

The liver strictly regulates its own volume relative to body mass. We aim to investigate and manipulate the mechanisms underlying this phenomenon. Based on increasing evidence that regeneration after partial hepatectomy (PHx) is triggered immediately by changes in hemodynamics, we have designe...

Tildelt: kr 1,2 mill.

Prosjektperiode: 2005-2007

Sted: Troms - Romsa - Tromssa

FOLKEHELSE-Folkehelse

Predictors of changes in depressive symptoms, suicidality, and eating problems in adolescence and early adulthood

Results are in conflict whether there has been an increase in adolescent internalizing problems (e.g. eating problems, depression, and suicidality) in the Western World during recent decades. Using identical procedures in 1992 and 2002, we ask whether sel f-reports of depressive symptoms, disorde...

Tildelt: kr 0,69 mill.

Prosjektperiode: 2005-2008

Sted: Oslo

RUSMIDDEL-Rusmiddelforskning

Drug abuse and psychosis: prevalence, clinical consequences and brain function.

Background: Patients with psychotic disorders are at a greater risk of having a drug abuse problem. Drug abuse is shown to worsen prognosis in psychotic disorders. Cannabis is, after alcohol, expected to be the most prevalent drug of abuse in our populati on. The biological association between ps...

Tildelt: kr 1,8 mill.

Prosjektperiode: 2005-2008

Sted: Oslo

TU-Tungt utstyr

Ultralydapparat for avansert klinisk forskning. Fellessøknad

Institutt for indremedisin, Universitetet i Bergen (UiB) har flere aktive forskningsgrupper som benytter avansert ultralyd-diagnostikk som den viktigste kliniske/eksperimentelle metode. Ultralyd-diagnostikk har over flere år vært et av satsningsområdene t il instituttet. Instituttets ultralydappa...

Tildelt: kr 2,3 mill.

Prosjektperiode: 2005-2006

Sted: Vestland

KLINISK-Klinisk forskning

Third International Stroke Trial in Norway

Thrombolytic treatment for acute stroke has recently been licensed for use in a few, highly selected patients, and under strict regulatory conditions. IST-3 is an independent international randomised-controlled trial designed to provide more reliable data on the effects of thrombolytic treatment...

Tildelt: kr 2,7 mill.

Prosjektperiode: 2005-2008

Sted: Ukjent Fylke

KLINISK-Klinisk forskning

Does benfotiamine reduce serum levels of advanced glycation end products and biochemical markers of vascular dysfunction in type 1 diabetes?

Background: Despite intensive efforts to improve glycemic control, diabetic patients are still at a markedly increased risk of microvascular complications associated with long-term hyperglycemia. Advanced glycation end prodcuts (AGEs) are thought to play a central role in the pathophysiology of t...

Tildelt: kr 1,6 mill.

Prosjektperiode: 2005-2007

Sted: Oslo

KREFTSATS-Særutlysning kreftmidler, historikk

Vaccination against B cell cancers: from experimental immunology to patients

Aim: The goal is to improve the prognosis of patients with multiple myeloma and B cell lymphoma by vaccination with a recombinant antibody-like vaccine (Vaccibodies). Background: B cell tumors produce a highly tumor-specific antigen, monoclonal immunoglob ulin with unique variable(V) regions, tha...

Tildelt: kr 3,8 mill.

Prosjektperiode: 2005-2008

Sted: Oslo

PSYKISK-Psykisk helse

The BDNF hypothesis of depression: a new framework for understanding depression and the actions of antidepressant drugs

Despite decades of research, the biological basis of major depression remains to be fully elucidated. Although antidepressants, such as serotonin reuptake inhibitors, rapidly increase serotonin levels in the extracellular space, the therapeutic effects of the drug are delayed by several weeks...

Tildelt: kr 3,3 mill.

Prosjektperiode: 2005-2008

Sted: Vestland

FRIMED-Klinisk medisin og folkehelse

Immune mechanisms and genetics associated with development of pre-eclampsia/eclampsia(PE/E)

PE is regarded as a two-step disease, with poor placentation and placental hypoperfusion as the first step in pathogenesis. The recognition of fetal trophoblasts by maternal uterine (uNK) cells is fundamental in placental development. Observations suggest that the superficial trophoblast invasio...

Tildelt: kr 2,0 mill.

Prosjektperiode: 2005-2007

Sted: Trøndelag - Trööndelage

FRIMED-Klinisk medisin og folkehelse

ACTIVE

Active is a prospective randomised trial of autologous chondrocyte transplantation compared with alternative treatments for patients who have had a failed primary treatment for chondral defect(s) in the knee. 660 patients in 14 cenres (12 in the UK, 2 in Norway) will be recruited over 2-3 years. ...

Tildelt: kr 0,90 mill.

Prosjektperiode: 2005-2007

Sted: Troms - Romsa - Tromssa

KREFTSATS-Særutlysning kreftmidler, historikk

MOLECULAR AND BIOLOGICAL STUDIES OF CANCER METASTASIS

Metastasis, cancer spread to other organs, is the principle cause of death of cancer patients. Early detection of metastatic tumor cells, development of new treatment strategies and knowledge about how to prevent cancer metastasis are some of the most cha llenging tasks in cancer research. Our pr...

Tildelt: kr 6,0 mill.

Prosjektperiode: 2005-2009

Sted: Oslo

KREFTSATS-Særutlysning kreftmidler, historikk

Novel therapeutic strategies for stimulation of anti-neoplastic immune activity

More than 20% of the human genome encodes proteins that are devoted to cellular signalling. Signal networks that involve the signal molecule cyclic AMP (cAMP) are involved in diseases such as cancer, cardiovascular disease, type II diabetes, obesity, HIV and asthma. Cyclic AMP acts as an acute in...

Tildelt: kr 6,0 mill.

Prosjektperiode: 2005-2007

Sted: Oslo

GLOBHELS-Global helse

The dual role of macrophages in mycobacterial- and HIV disease: host cell and generator of protective mediators with therapeutic potential.

HIV and Mycobacterium tuberculosis top the WHO list of deaths caused by infectious agents. Millons of people are co-infected, and drug resistance among pathogenic mycobacteria is a serious problem. To discover new therapies we need thorough knowledge abou t the interplay between the pathogens and...

Tildelt: kr 3,2 mill.

Prosjektperiode: 2004-2007

Sted: Trøndelag - Trööndelage

IS-RUS-Stipendprogram for NVRussl.

Alfarnes, Svein A RUS04/05 pva 7 forskere

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Tildelt: kr 60 000

Prosjektperiode: 2004-2005

Sted: Ukjent Fylke

FRIMED-Klinisk medisin og folkehelse

Zinc and common childhood infections - field trials in Nepal

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Tildelt: kr 2,2 mill.

Prosjektperiode: 2004-2007

Sted: Vestland

IS-SOE-Samarbeid med Sørøst- Europa

Terskeredzic, A. Albania SOE02-03-33 Erstatter Ercegovic 03/04

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Tildelt: kr 34 000

Prosjektperiode: 2004-2004

Sted: Ukjent Fylke

IS-RUS-Stipendprogram for NVRussl.

Suspitsin, E RUS03-04

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Tildelt: kr 40 000

Prosjektperiode: 2004-2004

Sted: Ukjent Fylke

YFF-Yngre, fremragende forskere

Toppforskningsprogrammets prosjekt ledet av Helga Refsum

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Tildelt: kr 0,81 mill.

Prosjektperiode: 2004-2005

Sted: Oslo

FRIMED-Klinisk medisin og folkehelse

Venous thromboembolism in pregnancy

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Tildelt: kr 1,5 mill.

Prosjektperiode: 2004-2008

Sted: Oslo

FRIMED-Klinisk medisin og folkehelse

Genetikk i klinisk onkologi: Ætioilogiske og terapeutiske undersøkelser hos pasienter med malign germinalcelletumor (MGCT)

Ekstragonadale germinalcelle tumores (EGCCT) representerer en klinisk viktig og vitenskapelig meget interessant undergruppe av maligne germinalcelle tumores (MGCT). Norge er nummer 2 på verdenstoppen hva insidens av disse svulster angår, og antall per år er økende uten at årsaken for denne øknin...

Tildelt: kr 1,8 mill.

Prosjektperiode: 2004-2008

Sted: Oslo

IS-NAD-Samarbeid med NORAD-land

Abd-Allah, Foad egyptisk statsstip 2004/05

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Tildelt: kr 0,12 mill.

Prosjektperiode: 2004-2005

Sted: Ukjent Fylke

FRIMED-Klinisk medisin og folkehelse

A study of global gene expression analysis to evaluate mammographic densities and risk for breast cancer

Høy mammografitetthet er en av de sterkeste kjente risikofaktorene for brystkreft. En vet lite om hva høy mammografitetthet innebærer på det molekylære plan, selv om det hevdes at det avspeiler brystcelleproliferasjon. Prosjektet ønsker å undersøke om de t er sammenheng mellom mammografitetthet ...

Tildelt: kr 1,8 mill.

Prosjektperiode: 2004-2010

Sted: Oslo

KREFTSATS-Særutlysning kreftmidler, historikk

Retinoids, antioxidants and cancer

Retinol and its metabolites (vitamin A, retinoids) orchestrates proliferation and differentiation through its nuclear retinoic acid receptors. Antioxidants have also recently been implied in regulation of cell signalling and gene transcription. There exis t convincing evidence that diets high in ...

Tildelt: kr 7,0 mill.

Prosjektperiode: 2004-2007

Sted: Oslo

IS-NABO-Nettverksprogram Norden-Næromr

Andres Jaigma, EE04, Nabo 04.05

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Tildelt: kr 0,12 mill.

Prosjektperiode: 2004-2005

Sted: Ukjent Fylke

IS-NABO-Nettverksprogram Norden-Næromr

Elina Hemminki, FI04, Nabo 04-05

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Tildelt: kr 0,25 mill.

Prosjektperiode: 2004-2005

Sted: Ukjent Fylke

YFF-Yngre, fremragende forskere

Identification of phenotypes and genetic susceptibility in severe mental disorders

Severe mental disorders (schizophrenia and bipolar/manic-depressive disorder) are major causes of disability worldwide, and rank as some of the most costly disorders to afflict humans. The etiology still remains elusive, but there is now overwhelming evid ence that genetic factors play a prominen...

Tildelt: kr 8,3 mill.

Prosjektperiode: 2004-2010

Sted: Oslo

IS-NABO-Nettverksprogram Norden-Næromr

Stig Örjan Ohlsson, EE11, Nabo 04-05

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Tildelt: kr 0,20 mill.

Prosjektperiode: 2004-2005

Sted: Ukjent Fylke

AKLIMED-Klinisk medisin

Utvikl. av Dobutamin STress Ekkokardiografi med en ny kvantitativ ultralydsmetode, Strain Rate Imaging Videreutvikling i Brisbane, Australia

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Tildelt: kr 0,29 mill.

Prosjektperiode: 2004-2005

Sted: Trøndelag - Trööndelage