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IS-BILAT-Mobilitet Norge-USA /Canada

Whole genome association analyses on a pre-eclampsia cohort-maternal genetic susceptibility and cardiovascular genetic/clinical profile

Pre-eclampsia (PE) is the most common pregnancy-associated complication in the Western world. The syndrome is a major contributor to maternal and fetal illness/death. No therapeutic treatment exists. The mechanisms involved in development of PE remain to be elucidated. The strong familial compo...

Tildelt: kr 0,25 mill.

Prosjektperiode: 2008-2009

Sted: Trøndelag - Trööndelage

FUGE-Funksjonell genomforskn.i Norg

Pathogenesis of complex genetic diseases, using pre-eclampsia as a model

Pre-eclampsia (PE) is the most common pregnancy-associated complication in the Western world. The syndrome is a major contributor to maternal and fetal illness/death. No therapeutic treatment exists. The mechanisms involved in development of PE remain to be elucidated. Observations suggest immu...

Tildelt: kr 8,5 mill.

Prosjektperiode: 2008-2013

Sted: Trøndelag - Trööndelage

FRIMED-Klinisk medisin og folkehelse

Immune mechanisms and genetics associated with development of pre-eclampsia/eclampsia(PE/E)

PE is regarded as a two-step disease, with poor placentation and placental hypoperfusion as the first step in pathogenesis. The recognition of fetal trophoblasts by maternal uterine (uNK) cells is fundamental in placental development. Observations suggest that the superficial trophoblast invasio...

Tildelt: kr 2,0 mill.

Prosjektperiode: 2005-2007

Sted: Trøndelag - Trööndelage

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