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FUGE-Funksjonell genomforskn.i Norg

Role of phosphorylation in regulation of redox-mediated events in apoptotic cell death

The blue-green algal toxins: nodularin and microcystin, induce apoptotic cell death in an ultrarapid manner (Fladmark et al., 1999). These toxins inhibit the general protein phosphatases (PP1 and PP2A) thereby resulting in Ca2+/calmodulin-dependent protei n kinase (CaMKII) hyperphosphorylation of...

Tildelt: kr 1,7 mill.

Prosjektperiode: 2006-2010

Sted: Vestland