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IS-BILAT-Mobilitet Norge-USA /Canada

Direct effects of sugar on development of cardiovascular disease

Based on epidemiological studies, elevated sugar consumption and chronic hyperglycemia is a risk factor for cardiovascular disease, partly due to systemic effects such as insulin resistance in hepatic, adipose and muscle tissue, type 2 diabetes, obesity a nd/or hypertension. However, it has now b...

Tildelt: kr 94 000

Prosjektperiode: 2013-2013

Sted: Oslo

FRIBIO-Biologi og biomedisin

Mechanisms of hyperglycemia-induced foam cell formation and atherosclerosis in type-2 diabetes. Role of the hexosamine biosynthetic pathway

Vascular disease is the most common cause of death in people suffering from type 2 diabetes. The high risk of atherosclerotic disease in type 2 diabetes can in part be accounted for by the diabetic state per se, such as hyperglycemia. Uptake of oxidised LDL and accumulation of cholesterol esters...

Tildelt: kr 3,1 mill.

Prosjektperiode: 2006-2009

Sted: Oslo

AB-MED1-Basal medisinsk forskning I

Atherosclerosis in obesity and type-2 diabetes: leptin and insulin signalling in macrophage foam cell formation

...

Tildelt: kr 2,1 mill.

Prosjektperiode: 2002-2004

Sted: Oslo

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