0 antall prosjekter

NEVRONOR-Nasjonal satsing på nevrovitenskap f

Attention deficit /hyperactivity disorder (ADHD): Risk factors, comorbidity and gene-environment interactions.

Attention deficit hyperactivity disorder (hyperkinetic disturbance; ADHD) is a common condition in school age children (world-wide prevalence estimates 3-7 %). In addition most affected individuals will continue to show symptoms as adults. Still, it has l ong been considered a controversial diagn...

Tildelt: kr 3,0 mill.

Prosjektperiode: 2007-2011

Sted: Vestland

PSYKISK-Psykisk helse

EARLY BIPOLAR DISORDER: CLINICAL AND BIOLOGICAL CHARACTERISTICS IN FIRST EPISODE MANIA

Bipolar disorder (BPD) is a severe psychiatric disorder characterized by manic and depressive episodes with periods of normal mood in between. Recent lines of evidence suggest that BPD is a more severe illness that previously believed and it is regarded as one of the most important factors contr...

Tildelt: kr 4,7 mill.

Prosjektperiode: 2007-2011

Sted: Oslo

KLINISK-Klinisk forskning

Patient education in patients with chronic obstructive pulmonary disease (COPD) and rheumatic disease: effect, experiences and costs

This is (hopefully) an improved version of an earlier application to NFR that was reviewed as both "a high quality research program" and "poorly written and non-competitive". The comments from the reviewers have been used to revise the project. Patient e ducation has become a task that is dictat...

Tildelt: kr 3,9 mill.

Prosjektperiode: 2007-2011

Sted: Trøndelag - Trööndelage

KLINISK-Klinisk forskning

Spontaneous firing activity in motoneurones of cervical paraspinal musculature in healthy subjects and in patients with neck pain

I prosjektet "Spontan elektrisk aktivitet i nerveceller til nakkemuskler hos friske frivillige og nakkesmertepasienter" forsøker vi å forstå mer av årsakene til nakkesmerter, ved å studere hvordan nerveceller i ryggmargen styrer nakkemusklene i ro og ved bevegelser. Vi ønsker å finne ut om disse...

Tildelt: kr 4,3 mill.

Prosjektperiode: 2007-2014

Sted: Oslo

FRIMEDBIO-Fri prosj.st. med.,helse,biol

Computational models of aberrant attribution of salience in schizophrenia and the effects of medication: An event related fMRI study

It has been known for decades that dopamine abnormalities are relevant to the pathophysiology of schizophrenia (mainly psychotic symptoms) and that blocking the dopamine system is associated with improvements in symptoms. How one gets from this neurochemi cal change to the expressed behavior abno...

Tildelt: kr 2,5 mill.

Prosjektperiode: 2007-2012

Sted: Oslo

KLINISK-Klinisk forskning

Genetic susceptibility and development of chronic sciatic pain - possible implications for future treatment

Previous findings suggest that development of chronic sciatic pain results from multiple functional changes in the peripheral and central nervous system. As described in this grant proposal, several recently described human genetic variants may affect suc h processes. Hence, individual genetic su...

Tildelt: kr 1,8 mill.

Prosjektperiode: 2007-2010

Sted: Oslo

IS-BILAT-Mobilitet Norge-USA /Canada

Determination of the naïve human EC cell transcriptome and identification of neoplastic genes in small intestinal carcinoids

Neuroendocrine tumors of the gut (carcinoids) represent a form of cancer that has not been rigorously studied, hence as a group such tumors are poorly understood, usually misdiagnosed and a logical treatment rationale is lacking. Small intestinal (EC) car cinoids, deriving from the enterochromaff...

Tildelt: kr 0,25 mill.

Prosjektperiode: 2007-2008

Sted: Trøndelag - Trööndelage

TU-Tungt utstyr

MULTICHANNEL ELECTROPHYSIOLOGICAL RECORDING FROM CELL ASSEMBLIES IN GENETICALLY MODIFIED BRAIN CIRCUITS

Despite impressive advances in every field of neuroscience, our understanding of brain function remains largely confined to its building blocks at the microscopic level, and to phenomenological descriptions at the macroscopic level. The introduction of tr ansgenic mice has provided neuroscience w...

Tildelt: kr 1,8 mill.

Prosjektperiode: 2007-2007

Sted: Trøndelag - Trööndelage

NEVRONOR-Nasjonal satsing på nevrovitenskap f

Norwegian PET Conference and Seminar Series

This application is for fundiing for conference and seminar series to develop the Positron emission tomography (PET) method into an important tool in the study of the Brain and Brain-derived human disease. It is based on the Norwegian Medical Cyclotron Ce nter (NMS) in Oslo and the Bergen PET Cen...

Tildelt: kr 0,30 mill.

Prosjektperiode: 2007-2009

Sted: Oslo

NEVRONOR-Nasjonal satsing på nevrovitenskap f

Quantitative MR imaging used to gain new knowledge of perinatal brain injury- from newborns to young adults with very low birth weight

The neurological adult outcome of VLBW and ELBW survivors is of great interest to society. Perinatal brain injury has major impact both economically, for health care and emotionally for parents and children as they develop into adulthood. Combining quanti tative MRI and clinical research, may ser...

Tildelt: kr 2,9 mill.

Prosjektperiode: 2007-2012

Sted: Trøndelag - Trööndelage

TU-Tungt utstyr

Magnetic resonance imaging and spectroscopy of small animals

Magnetic Resonance Imaging (MRI) offers unique opportunities to obtain in vivo information about organ structure and function. The technique is widely used in clinical research. This application from several research groups at Ullevaal University Hospital is primarily focussed on the neurobiolog...

Tildelt: kr 5,3 mill.

Prosjektperiode: 2007-2009

Sted: Oslo

FRIMEDBIO-Fri prosj.st. med.,helse,biol

Improved individualized diagnosis and treatment monitoring of prostate and breast cancer by combining new MR and ultrasound technology

This project deals with combining new methods in medical ultrasound (US) and Magnetic Resonance (MR) imaging to improve individualized diagnosis and treatment monitoring of prostate and breast cancer. The project includes further development of new techno logy and taking this technology into clin...

Tildelt: kr 3,7 mill.

Prosjektperiode: 2007-2012

Sted: Trøndelag - Trööndelage

S-AFRIKA-Program for forskningsamarbeid med Sør- Afrika

DDT and "current use pesticides" in mothers and children in a malaria control area in South Africa

The effects of environmental pollutants on human health are often subtle, long-term, sometimes transgenerational and difficult to measure even in long-term epidemiological studies in large populations. There is therefore a need for comprehensive research that monitors the concentration and distri...

Tildelt: kr 0,61 mill.

Prosjektperiode: 2007-2010

Sted: Akershus

FOLKEHELSE-Folkehelse

Energy Balance and Breast Cancer Aspects. A randomised clinical trial with physical activity interventio

Breast cancer requires intense and prolonged treatments often associated with significant side effects, also influencing their levels of physical activity after diagnosis. New evidence from large cohort studies supports a role of physical activity in redu cing recurrence and improving survival. A...

Tildelt: kr 2,6 mill.

Prosjektperiode: 2007-2011

Sted: Oslo

KLINISK-Klinisk forskning

Does fusion lead to increased adjacent level disc degeneration in patients with chronic low back pain. An international collaborate project.

There is controversy as to whether fusion of one or more motion segments of the spine results in accelerated degeneration of the adjacent segment over time. Some argue that adjacent segment is exposed to increased mechanical stress, which accelerates disc degeneration, whilst others maintain tha...

Tildelt: kr 3,9 mill.

Prosjektperiode: 2007-2011

Sted: Oslo

KLINISK-Klinisk forskning

Stimulating self-management in patients with fibromyalgia syndrome through web-based situational feedback

Self-management of chronic pain is increasingly seen as an important tool in providing adequate care to patients with Fibromyalgia Syndrome (FMS) and other types of Chronic Non-malignant Pain. Enhancing the patient's self-management of his condition is th ought to be effective in reducing pain an...

Tildelt: kr 3,4 mill.

Prosjektperiode: 2007-2012

Sted: Oslo

IS-NAD-Samarbeid med NORAD-land

El-Komy, Mohamed Egyptisk spes 2007

...

Tildelt: kr 25 701

Prosjektperiode: 2007-2007

Sted: Oslo

IS-NAD-Samarbeid med NORAD-land

Nada, Ahmed egyptisk spes 2007

...

Tildelt: kr 21 203

Prosjektperiode: 2007-2007

Sted: Trøndelag - Trööndelage

IS-NAD-Samarbeid med NORAD-land

Mohsen, Amr egyptisk spes 2007

...

Tildelt: kr 21 203

Prosjektperiode: 2007-2007

Sted: Trøndelag - Trööndelage

FRIMED-Klinisk medisin og folkehelse

Immunopathogenic mechanisms in coronary artery disease

Despite state of the art cardiovascular treatment, coronary artery disease (CAD) with development of acute coronary syndromes are still common manifestations of atherosclerosis, suggesting that important pathogenic mechanisms remain active and unmodified by the present treatment modalities. Based...

Tildelt: kr 2,3 mill.

Prosjektperiode: 2007-2011

Sted: Oslo

FRIMEDBIO-Fri prosj.st. med.,helse,biol

Targeting occult tumor cell dissemination in localised breast cancer

For the future, a better treatment of patients with breast cancer is dependent upon a better assessment of the individual risk of harbouring minimal residual disease after the completion of the surgical treatment. The aim is to separate very low risk pati ents from high risk patients for future m...

Tildelt: kr 2,5 mill.

Prosjektperiode: 2007-2012

Sted: Oslo

NEVRONOR-Nasjonal satsing på nevrovitenskap f

The Norwegian Multiple Sclerosis Registry and Biobank

Multiple sclerosis (MS) is an immune-mediated, inflammatory disease of the central nervous system (CNS) in genetically susceptible individuals. It is a disabling disease of young adults, with no curable treatment available. There is growing knowledge of s everal aspects of the disease, but the et...

Tildelt: kr 4,5 mill.

Prosjektperiode: 2007-2010

Sted: Vestland

FRIMED-Klinisk medisin og folkehelse

Combined structural, microvascular and functional mapping of brain tumors for improved diagnosis and treatment planning

During recent years, the department of radiology at Rikshospitalet-Radiumhospitalet (RR) Medical Center has had a strong focus on functional MRI (Magnetic Resonance Imaging) research; including perfusion/ diffusion MRI and spectroscopy, with the aim of br inging novel MR techniques into early cli...

Tildelt: kr 2,2 mill.

Prosjektperiode: 2007-2010

Sted: Oslo

IS-RUS-Stipendprogram for NVRussl.

Rezvyy, G RUS06/07-119

...

Tildelt: kr 30 000

Prosjektperiode: 2007-2008

Sted: Ukjent Fylke

FRIMED-Klinisk medisin og folkehelse

Molecular and clinical aspects of cancer

...

Tildelt: kr 1,5 mill.

Prosjektperiode: 2007-2009

Sted: Troms - Romsa - Tromssa

FRIMED-Klinisk medisin og folkehelse

L-Ornithine and phenylacetate: A novel and effective therapy for hepatic encephalopathy

Background: The major therapeutic target for the treatment of hepatic encephalopathy is ammonia. Our extensive investigations in animal models and also in humans with cirrhosis support the view that the major organ removing ammonia in patients with cirrho sis is the muscle, converting ammonia to ...

Tildelt: kr 1,3 mill.

Prosjektperiode: 2007-2009

Sted: Troms - Romsa - Tromssa

FRIMED-Klinisk medisin og folkehelse

The Tromsø Pain Study: Causes and consequences of individual differences in pain sensitivity

Human pain sensitivity is subject to very large inter-individual variation. It is known that pain sensitivity is heritable, but the genes involved are largely unknown. Hypersensitivity to pain may be an important risk factor in the development, maintenanc e and consequences of chronic pain. Reduc...

Tildelt: kr 3,7 mill.

Prosjektperiode: 2007-2010

Sted: Oslo

FRIMED-Klinisk medisin og folkehelse

Hepatocyte Growth Factor (HGF)-signalling as target for treatment of multiple myeloma

Multiple myeloma is due to clonal expansion of malignant plasma cells. The incidence in the Nordic countries is approximately 6 new cases per 100,000 per year, which corresponds to nearly 20% of hematological cancers. Approximately 300 persons are given t his diagnosis each year in Norway. An imp...

Tildelt: kr 2,2 mill.

Prosjektperiode: 2007-2008

Sted: Trøndelag - Trööndelage

TU-Tungt utstyr

Functional Neuroanatomy of the Cortico-Parahippocampal-Hippocampal Memory System.

Memory is a property of distributed networks in the mammalian cortex. While the permanent storage of episodic memories is likely to take place at distributed locations in the neocortex, fast acquisition of such memories depends critically on the (para)hip pocampal system. This dependence reflects...

Tildelt: kr 6,8 mill.

Prosjektperiode: 2007-2010

Sted: Trøndelag - Trööndelage

IS-RUS-Stipendprogram for NVRussl.

Suborov, E RUS06/07-79

...

Tildelt: kr 44 500

Prosjektperiode: 2006-2007

Sted: Troms - Romsa - Tromssa