0 antall prosjekter

Dato fra ny til gammel

GLOBHELS-Global helse

A rapid serological screening method for detecting tuberculosis disease and monitoring the efficacy of new vaccines

The development of new diagnostic tools and more effective vaccines are essential to combat the global tuberculosis (TB) pandemic. The lack of a widely accessible screening test that is easy to perform without laboratory facilities is one of the main reas ons for the unacceptable delay in diagnos...

Tildelt: kr 12,8 mill.

Prosjektperiode: 2009-2013

Sted: Oslo

BIA-Brukerstyrt innovasjonsarena

Genetic and Process Optimizations for Effective Screening and Functional Production of Novel Therapeutic Antibody Fragments

The application range of antibodies in medicine and biotechnology is broad and there is a huge progress in the design and selection of new variants with novel properties. Affitech is a relative young biotech company founded in 1997, and is still establish ed in the international forefront of disc...

Tildelt: kr 4,0 mill.

Prosjektperiode: 2009-2011

Sted: Oslo

FRIMEDBIO-Fri prosj.st. med.,helse,biol

Hip fractures: Predictors, incidence and survival. NOREPOS: The Norwegian Epidemiological Osteoporosis Studies

Hip fractures in Norway 1999-2008: time trends in total incidence and second hip fracture rates: a NOREPOS study. Eur J Epidemiol. 2012 Oct;27(10):807-14. doi: 10.1007/s10654-012-9711-9. Epub 2012 Jun 30 Norge har en av verdens høyeste rapporterte forek omst av hoftebrudd. Flere vestlige land ra...

Tildelt: kr 9,2 mill.

Prosjektperiode: 2009-2015

Sted: Vestland

RUSMIDDEL-Rusmiddelforskning

Women maintained on opioid drugs in pregnancy. Investigation of outcomes for mother and child. Evaluation of care and follow up.

Heroin dominated substance abuse is a world wide phenomenon. The dominating treatment approach is opioid maintenance treatment (OMT) based on continuing use of methadone or buprenorphine. As a consequence an increasing number of children is exposed to h igh levels of opioid drugs within uterus ...

Tildelt: kr 4,0 mill.

Prosjektperiode: 2009-2013

Sted: Oslo

PSYKISK-Psykisk helse

Regulation of emotion in children with ADHD- a longitudinal study

We aim to recruit 30 children with a combined type of attention deficit/hyperactivity-disorder (ADHD) and 30 controls aged 9-12 years. The children will go through a careful clinical characterization, neuropsychological testing, MR scanning and measuring of ERP's. The participants will receive tr...

Tildelt: kr 3,8 mill.

Prosjektperiode: 2009-2013

Sted: Vestland

FRIMEDBIO-Fri prosj.st. med.,helse,biol

Causes of autism spectrum disorders. Epidemiologic studies based on MoBa, the ABC Study and the Autism Database.

Autismespekterforstyrrelser (ASF) har fått mye oppmerksomhet den senere tid som følge av observert økt forekomst i høyinntektsland, og spekulasjoner rundt en mulig årsakssammenheng med vaksiner eller andre eksponeringsfaktorer i miljøet. Kunnskapen om årsaker til ASF er imidlertid begrenset. Heru...

Tildelt: kr 4,0 mill.

Prosjektperiode: 2009-2016

Sted: Oslo

KREFT-Offentlig kreftprogram

Somatic, translational and psychosocial research in long-term cancer survivors

Background: The number of long-term cancer survivors (LTCSs) (>5 years after primary treatment) is rapidly increasing and currently concerns >100,000 patients in Norway. Although frequently cured by their disease, the treatments and the cancers have late effects that impair the physical and ment...

Tildelt: kr 5,2 mill.

Prosjektperiode: 2009-2015

Sted: Oslo

RUSMIDDEL-Rusmiddelforskning

Neurocognitive development in children born to mothers with substance abuse and psychiatric disorders: biological-social interaction effects

Mye tid og ressurser i prosjektet har blitt brukt til rekruttering og undersøkelse av deltagere. Dette er en spesiell gruppe barn, som det kreves stor innsats å få kontakt med. Likevel gikk rekrutteringen og gjennomføringen av undersøkelsene har likevel som forventet. Hovedformålet med prosjek...

Tildelt: kr 6,0 mill.

Prosjektperiode: 2009-2014

Sted: Oslo

RUSMIDDEL-Rusmiddelforskning

COGNITIVE FUNCTION AND NEUROBIOLOGICAL ASSESSMENT OF MEDICATION ASSISTED REHABILITATION

Drug addiction is a chronically relapsing disorder and heroin dependence is still a challenge with devastating impact on both the individual and the society. Medication assisted rehabilitation is offered by our health care system to treat opioid dependenc e and to prevent relapse. Opioid maintena...

Tildelt: kr 6,6 mill.

Prosjektperiode: 2009-2012

Sted: Oslo

KREFTSATS-Særutlysning kreftmidler, historikk

Translational research directed toward identification of the mechanisms of chemoresistance in breast cancer.

Our group conducts translational research with the primary aim of identifying the mechanisms of resistance to chemotherapy in breast cancer. We have concentrated our work on alterations in genes participating in the p53 and retinoblastoma protein pathway as cause of anthracycline resistance. In ...

Tildelt: kr 3,6 mill.

Prosjektperiode: 2009-2012

Sted: Vestland

BIA-Brukerstyrt innovasjonsarena

A gene expression signature for the early detection of Parkinson disease

The diagnosis of PD today relies on a physicians exam. Autopsy studies, however, have demonstrated that even experienced neurologists misdiagnose PD in about a quarter out of a hundred cases. Diagnostic accuracy at disease onset, when neuroprotective trea tment is anticipated to be most effective...

Tildelt: kr 5,0 mill.

Prosjektperiode: 2009-2013

Sted: Oslo

NEVRONOR-Nasjonal satsing på nevrovitenskap f

Molecular labels that instruct specific synapse formation

One of the major questions within the field of Molecular Neuroscience is how different neurons are able to locate and form synapses specifically with their appropriate targets so that functional neural circuits are generated. Two quite different mechanis ms appear to be involved. One is an activ...

Tildelt: kr 42 999

Prosjektperiode: 2009-2009

Sted: Oslo

BIA-Brukerstyrt innovasjonsarena

Double sided silicon strip detection (DSSD) technology applied in cancer research

The primary objective of this project is to achieve a Biomolex product for identifying the role of protein kinases in cancer diseases. This product will open up the market for Biomolex within the cancer research field. This will be done through developmen t of both software and tailored and gener...

Tildelt: kr 5,2 mill.

Prosjektperiode: 2009-2011

Sted: Oslo

BIA-Brukerstyrt innovasjonsarena

A novel antimicrobial agent for treatment of infections caused by drug-resistant bacteria, preclinical and early phase clinical studie

The present proposal covers preclinical exploratory and Phase I/IIa development programme of LTX-109. The proposal encompasses our internal development program as well as the establishment and management of external production and development programs. L ytix Biopharma AS develop novel antimicro...

Tildelt: kr 8,3 mill.

Prosjektperiode: 2009-2011

Sted: Oslo

BIA-Brukerstyrt innovasjonsarena

Utvikling av diagnostikk for påvisning av latent og aktiv tuberkuloseinfeksjon

Tuberkulose (TB) er en av de store globale helseutfordringene og bekjempelse av sykdommen er omfattet av FN's tusenårsmål. Om lag 2 milliarder av verdens befolkning er i dag infisert med TB i latent eller aktiv form. Tall fra 2006 viser at 9,2 millioner m ennesker blir syke av TB årlig, hvorav 1,...

Tildelt: kr 2,6 mill.

Prosjektperiode: 2009-2012

Sted: Oslo

BIA-Brukerstyrt innovasjonsarena

Cardiac and respiratory monitoring utilizing UWB-IR technology

The main goal in this project is a cardiac and respiratory monitoring radar. The radar will be based upon Ultra Wide Band Impulse Radar (UWB-IR) technology. It will have reduced power consumption, be miniaturized, wireless, detached monitoring, robust det ection, and small in size compared to exi...

Tildelt: kr 6,2 mill.

Prosjektperiode: 2009-2011

Sted: Oslo

PSYKISK-Psykisk helse

Longitudinal MRI Studies of Brain Morphology in Schizophrenia and Bipolar Disorder: Etiological Risk and Genetic Association.

Schizophrenia is often considered being a neurodevelopmental disease. The phenotype is heterogeneous with high heritability (80%) and unknown etiology and pathophysiology. Morphological brain abnormalities appear to be intrinsic features of the disease. I n previous scientific studies, abnormalit...

Tildelt: kr 5,4 mill.

Prosjektperiode: 2009-2013

Sted: Oslo

FRIMEDBIO-Fri prosj.st. med.,helse,biol

Hepatocyte Growth Factor in the Pathogenesis of Multiple Myeloma

Since our publications in 1996 showing that malignant plasma cells (MM cells) usually express both HGF and its receptor c-Met, a growing number of reports have implicated HGF/c-Met in the biology of MM. For instance, high levels of HGF in serum of MM pati ents predict a bad prognosis and correlat...

Tildelt: kr 3,3 mill.

Prosjektperiode: 2009-2012

Sted: Trøndelag - Trööndelage

FORNY-3-Kommersialisering av FoUresultater

A new therapeutic strategy to combat antibiotic resistance

...

Tildelt: kr 1,4 mill.

Prosjektperiode: 2009-2010

Sted: Oslo

FRIMEDBIO-Fri prosj.st. med.,helse,biol

Spatiotemporal Regulation of cAMP Signalling in Health and Disease

Signalling networks involving the signal molecule cAMP and protein kinase A (PKA) are involved in regulation of a multitude of body functions involving most organ systems of the body. An emerging principle is that function of the cAMP signal pathway in th ese settings requires subcellular anchori...

Tildelt: kr 6,0 mill.

Prosjektperiode: 2009-2014

Sted: Oslo

GLOBHELS-Global helse

Development of an outer membrane vesicle vaccine for Africa against serogroup A and W-135 meningococcal disease

Epidemics of meningococcal disease are a significant health problem in most African countries, and there is a strong need for improved and affordable vaccines. We are here proposing a collaborative program between Norway, Cuba and Ethiopia to provide a ne w approach for prevention of bacterial me...

Tildelt: kr 6,7 mill.

Prosjektperiode: 2009-2014

Sted: Oslo

FORNY-3-Kommersialisering av FoUresultater

Tumor Target Therapy with Immunotoxin and Cyclosporin A - a phase I study in patients with advanced carcinoma

...

Tildelt: kr 0,64 mill.

Prosjektperiode: 2009-2010

Sted: Oslo

STAMCELLER-Stamcelleforskning

Tissue engineering of hyaline cartilage

Cartilage injuries are frequent and lead to pain and disability. Unfortunately, articular cartilage shows a limited capacity for selfhealing and often goes on to osteoarthritis. Several surgical techniques have been developed to fill the cartilage defects , but so far none of them have been able ...

Tildelt: kr 7,7 mill.

Prosjektperiode: 2009-2013

Sted: Oslo

NEVRONOR-Nasjonal satsing på nevrovitenskap f

Causes of MS and MG. Search for susceptibility factors of multiple sclerosis and myasthenia gravis

Background: Multiple sclerosis (MS) is a presumed autoinflammatory disorder of the central nervous system. Myastenia gravis (MG) is also an autoimmune neurologic disease, affecting the Achetyl choline receptor (AChR) postsynaptic in the muscle-nerve junct ion. Common for both diseases is that the...

Tildelt: kr 1,9 mill.

Prosjektperiode: 2009-2013

Sted: Oslo

NEVRONOR-Nasjonal satsing på nevrovitenskap f

Second International Conference on Imaging in Neuroscience

It is applied for a conference on imaging in neuroscience research in Tromsø 14-15/5 2009. The aim of the conference is to establish contacts between researchers, firstly at a national, but also at an international level. The conference will target areas that are relevant for ongoing research in ...

Tildelt: kr 0,40 mill.

Prosjektperiode: 2009-2009

Sted: Troms - Romsa - Tromssa

FORNY20-FORNY2020

Cardio-protective Factor in Myocardial Ischemia/Reperfusion Injury and Heart Failure

...

Tildelt: kr 2,5 mill.

Prosjektperiode: 2009-2011

Sted: Oslo

FRIMEDBIO-Fri prosj.st. med.,helse,biol

Neurogenetics of aging: impact of DNA repair on Alzheimer disease

The genetic background for cognitive loss, dementia and aging processes is poorly described, and multidisciplinary research is needed to increase this knowledge. Alzheimer disease (AD) is by far the most important contributor to cognitive decline and deme ntia worldwide. Incidence may quadruple s...

Tildelt: kr 4,1 mill.

Prosjektperiode: 2009-2013

Sted: Oslo

FORNY-3-Kommersialisering av FoUresultater

New Drugs for Treatment of Cerebral Edema

...

Tildelt: kr 1,8 mill.

Prosjektperiode: 2009-2010

Sted: Oslo

FORNY-3-Kommersialisering av FoUresultater

Pepbody - verification of potential as as new drug for the treatment of autoimmune inflammatory disorders

...

Tildelt: kr 0,98 mill.

Prosjektperiode: 2009-2010

Sted: Oslo

FORNY-3-Kommersialisering av FoUresultater

Prevention and Treatment of Sepsis

...

Tildelt: kr 1,1 mill.

Prosjektperiode: 2009-2009

Sted: Oslo

1 14 15 16 17 18 23