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EIC-The European Innovation Council (EIC)

Development of innovative proton and neutron therapies with high cancer specificity by 'hijacking' the intracellular chemistry of haem biosynthesis.

Deep-lying cancers, such as glioblastoma multiforme (GBM) brain cancer, are very difficult to access and incurable by the current standards of care. The fluorescence of photosensitive molecules (PSs) can precisely guide surgical resection of GBM. Nevertheless, photomedical treatments like photody...

Tildelt: kr 25,2 mill.

Prosjektperiode: 2024-2028

Sted: Oslo

CL1-Health

Multimodal 3D Holographic tool and real-time Guidance System with point-of-care diagnostics for surgical planning and interventions on liver and pancreatic cancers

Multimodal 3D Holographic tool and real-time Guidance System with point-of-care diagnostics for surgical planning and interventions on liver and pancreatic cancers

Tildelt: kr 44,6 mill.

Prosjektperiode: 2024-2027

Sted: Oslo og 2 andre

MSCA-Marie Sklodowska-Curie Actions (MSCA)

DSTrain - Data Science Postdoctoral Training Programme

DSTrain is a 5-year postdoctoral programme that will award 36 postdoctoral fellowship positions of 36 months each in two calls over the programme period within the overarching frame of data science. The programme will train researchers and innovators with disciplinary, interdisciplinary and trans...

Tildelt: kr 52,1 mill.

Prosjektperiode: 2024-2028

Sted: Akershus og 12 andre

CL1-Health

ENTEROVIRUS-LINKED TYPE 1 DIABETES EXPOSED -MECHANISMS AND PREVENTION

ENT1DEP aims to define causal links between infections and NCDs by focusing on enterovirus (EV) infections and type 1 diabetes (T1D), a robust association without proof of causality. Causality is addressed by a multidisciplinary, multi-layer approach, using in-vitro and in-vivo models, unique hum...

Tildelt: kr 7,3 mill.

Prosjektperiode: 2024-2027

Sted: Oslo

CL1-Health

The malignant Glioma immuno-oncology matchmaker: towards data-driven precision medicine using spatially resolved radio-multiomics

The malignant Glioma immuno-oncology matchmaker: towards data-driven precision medicine using spatially resolved radio-multiomics

Tildelt: kr 12,2 mill.

Prosjektperiode: 2024-2028

Sted: Oslo

CL1-Health

Targeting Epstein-Barr Virus Infection for Treatment and Prevention of Multiple Sclerosis

Targeting Epstein-Barr Virus Infection for Treatment and Prevention of Multiple Sclerosis

Tildelt: kr 29,6 mill.

Prosjektperiode: 2023-2028

Sted: Oslo og 5 andre

CL5-Climate, Energy and Mobility

From solar energy to fuel: A holistic artificial photosynthesis platform for the production of viable solar fuels

From solar energy to fuel: A holistic artificial photosynthesis platform for the production of viable solar fuels

Tildelt: kr 21,8 mill.

Prosjektperiode: 2023-2027

Sted: Akershus og 2 andre

ERC-European Research Council (ERC)

Targeting Acute Leukemia with TdT-TCR-T-cell therapy

The aim of this PoC project is to commercialize new therapy for acute lymphoblastic leukemia (ALL) developed in context of my ERC consolidator grant. T-cell receptors (TCRs) have in recent years emerged as promising therapeutic molecules in cell- and gene-therapy of cancer. I have completed the p...

Tildelt: kr 1,7 mill.

Prosjektperiode: 2023-2025

Sted: Oslo og 2 andre

CL1-Health

PRecisIon Cancer MEdicine RepurpOsing SystEm Using Pragmatic Clinical Trials

PRecisIon Cancer MEdicine RepurpOsing SystEm Using Pragmatic Clinical Trials

Tildelt: kr 18,2 mill.

Prosjektperiode: 2023-2028

Sted: Oslo

CL1-Health

Reconstruction and Computational Modelling for Inherited Metabolic Diseases

Reconstruction and Computational Modelling for Inherited Metabolic Diseases

Tildelt: kr 0,10 mill.

Prosjektperiode: 2023-2027

Sted: Oslo

CL1-Health

International Study for Treatment of Childhood Relapsed ALL 2020

International Study for Treatment of Childhood Relapsed ALL 2020

Tildelt: kr 1,1 mill.

Prosjektperiode: 2023-2028

Sted: Oslo

CL1-Health

COMPREHENSIVE CANCER INFRASTRUCTURES 4 EUROPE

Cancer is the second leading cause of death in Europe with an expected increase of about 25% by 2035. A wide and unacceptable variability in terms of access to research, innovation and quality care exists between and within countries. Possible solutions are an increase in knowledge by funding res...

Tildelt: kr 3,2 mill.

Prosjektperiode: 2023-2026

Sted: Oslo

CL1-Health

IMPlementing geriatric assessment for dose Optimization of CDK 4/6-inhibitors in older bReasT cAncer patieNTs

Current evidence from both randomized trials and real-world evidence studies suggests that older breast cancer patients derive clinical benefit from the addition of CDK 4/6-inhibitors to endocrine therapy but with higher risk for adverse events and treatment discontinuation compared to younger pa...

Tildelt: kr 3,7 mill.

Prosjektperiode: 2023-2028

Sted: Akershus

CL1-Health

Establishing of Cancer Mission Hubs: Networks and Synergies

Establishing of Cancer Mission Hubs: Networks and Synergies

Tildelt: kr 3,7 mill.

Prosjektperiode: 2023-2026

Sted: Oslo og 3 andre

MSCA-Marie Sklodowska-Curie Actions (MSCA)

Guiding glioblastoma treatments by decrypting tumor biomechanics via Magnetic Resonance Elastography.

Glioblastoma multiforme (GBM) is the most common and deadly type of primary brain tumour, carrying a dire prognosis with a median survival of 14.6 months for patients undergoing standard treatments. The causes of poor clinical prognosis are late diagnosis, diffuse infiltration, pseudo necrosis, h...

Tildelt: kr 2,9 mill.

Prosjektperiode: 2023-2026

Sted: Oslo

MSCA-Marie Sklodowska-Curie Actions (MSCA)

Combination therapy for the treatment of metastatic melanoma using magnetic nanoparticles

Metastatic melanoma is a hard-to-treat disease and it remains as one of the most worrisome cancer. There is an urgent need to improve the current therapies (chemotherapy, radiotherapy) that have a limited efficacy. A single therapy is not efficient to tackle metastatic melanoma and a combination ...

Tildelt: kr 3,0 mill.

Prosjektperiode: 2023-2027

Sted: Oslo

ERC-European Research Council (ERC)

Final act of the autophagy symphony: Whole-organism orchestration of autophagy termination

Final act of the autophagy symphony: Whole-organism orchestration of autophagy termination

Tildelt: kr 15,2 mill.

Prosjektperiode: 2023-2027

Sted: Oslo

WIDENING-Widening participation and spreading excellence

Diabetes, obesity and the Kidney

Chronic kidney disease is a major cause of morbidity and mortality in the EU. About 10-15% of the EU population has chronic kidney disease (CKD) and this number is expected to increase in the future decades. Diabetes is today the main cause of CKD in the EU: about, 30% of the cases with dialysi...

Tildelt: kr 2,9 mill.

Prosjektperiode: 2023-2025

Sted: Oslo

CL1-Health

Quality of Life in Oncology: measuring what matters for cancer patients and survivors in Europe

EUonQoL aims to develop, pilot and validate the EUonQoL-Kit, a patient-driven, unified system for the assessment of quality of life (QoL) based on evaluations and preferences of cancer patients and survivors. The EUonQoL-Kit will be developed from a patient perspective, administered digitally, av...

Tildelt: kr 7,6 mill.

Prosjektperiode: 2023-2026

Sted: Oslo

CL1-Health

Maximising Impact of Prescription Drugs in Rheumatoid Arthritis

Maximising Impact of Prescription Drugs in Rheumatoid Arthritis

Tildelt: kr 21,1 mill.

Prosjektperiode: 2022-2027

Sted: Oslo

EIC-The European Innovation Council (EIC)

Supervised morphogenesis in gastruloids

The lack of realistic in vitro organ models that can faithfully represent in vivo physiological processes is a major obstacle affecting the biological and medical sciences. The current gold standard is animal experiments, but it is increasingly clear that these models mostly fail to recapitulate ...

Tildelt: kr 13,6 mill.

Prosjektperiode: 2022-2027

Sted: Oslo

CL1-Health

Psych-STRATA - A Stratified Treatment Algorithm in Psychiatry: A program on stratified pharmacogenomics in severe mental illness

Psych-STRATA - A Stratified Treatment Algorithm in Psychiatry: A program on stratified pharmacogenomics in severe mental illness

Tildelt: kr 6,6 mill.

Prosjektperiode: 2022-2027

Sted: Oslo

CL1-Health

Intelligent Ecosystem to improve the governance, the sharing and the re-use of health Data for Rare Cancers

Intelligent Ecosystem to improve the governance, the sharing and the re-use of health Data for Rare Cancers

Tildelt: kr 3,6 mill.

Prosjektperiode: 2022-2026

Sted: Oslo

CL1-Health

OPTIMISING COLORECTAL CANCER PREVENTION TROUGH PERSONALISED TREATMENT WITH ARTIFICIAL INTELLIGENCE

Integration of artificial intelligence (AI) technologies into clinical medicine has been hampered by challenges related to uncertain long-term clinical benefits, cost-effectiveness, and ethics/legal concerns. Application of AI in colonoscopy, a forefront research topic, has been also bothered by ...

Tildelt: kr 32,0 mill.

Prosjektperiode: 2022-2027

Sted: Oslo

CL1-Health

Implementing a patient-centred and evidence-based intervention to reduce BEnzodiazepine and sedative-hypnotic use to improve patient SAFEty and quality of care

Benzodiazepine and sedative hypnotics (BSHs) incur significant adverse effects and costs, especially in older adults. Addressing BSH overuse in older adults is therefore an urgent priority to improve patient safety in Europe. However, previous attempts did not lead to large-scale reduction in use...

Tildelt: kr 11,1 mill.

Prosjektperiode: 2022-2027

Sted: Oslo

CL1-Health

Developing and implementing innovative Patient-Centred Care Pathways for cancer patients

Developing and implementing innovative Patient-Centred Care Pathways for cancer patients

Tildelt: kr 22,9 mill.

Prosjektperiode: 2022-2027

Sted: Telemark og 3 andre

MSCA-Marie Sklodowska-Curie Actions (MSCA)

Training the next-generation of European GLIOblastoma (translational) researchers, to RESOLVE precision targeting of the brain tumour microenvironment

Isocitrate dehydrogenase wildtype (IDHwt) glioblastoma (GBM) is the most frequent, aggressive and lethal brain tumour. It has a universally fatal prognosis with 85% of patients dying within two years. Effective precision medicine therapies are thus urgently required. This can only be achieved by ...

Tildelt: Skjult

Prosjektperiode: 2022-2026

Sted: Oslo

CL1-Health

A clinical research network to improve the management of Monkeypox virus disease

A clinical research network to improve the management of Monkeypox virus disease

Tildelt: kr 6,6 mill.

Prosjektperiode: 2022-2026

Sted: Oslo

CL1-Health

Dual screening by Spectral Artificial Visual Examination (SAVE) for Female Genital Schistosomiasis (FGS) and cervical cancer. Digital, new, low-cost, and simple screening and training.

Dual screening by Spectral Artificial Visual Examination (SAVE) for Female Genital Schistosomiasis (FGS) and cervical cancer. Digital, new, low-cost, and simple screening and training.

Tildelt: kr 34,8 mill.

Prosjektperiode: 2022-2026

Sted: Agder og 2 andre

CL1-Health

Gene-edited T cells combating IgA Nephropathy. A blueprint approach for safe & efficient genome editing of T cells to sustainably combat several immune diseases and cancers related to B-cell pathology

Gene-edited T cells combating IgA Nephropathy. A blueprint approach for safe & efficient genome editing of T cells to sustainably combat several immune diseases and cancers related to B-cell pathology

Tildelt: kr 5,6 mill.

Prosjektperiode: 2022-2026

Sted: Oslo

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