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Dato fra ny til gammel

YFF-Yngre, fremragende forskere

Lipocalin 2 - a novel antimicrobial protein: Role in mycobacterial disease, urinary tract infection and in wound healing

Infectious diseases remain the main cause of premature death worldwide and antimicrobial resistance is increasing. Consequently, the WHO stresses that there is an urgent need for new drugs and supplementary treatment regimens against infectious agents. We have recently discovered a novel mechani...

Tildelt: kr 8,2 mill.

Prosjektperiode: 2007-2013

Sted: Trøndelag - Trööndelage

GLOBHELS-Global helse

Immunity towards mycobacteria - identification of avirulent vaccine strains and therapeutic targets

Tuberculosis (TB) kills nearly 2 million people each year, and, together with HIV, Mycobacterium tuberculosis top the WHO list of deaths caused by infectious agents. In HIV infected individuals, Mycobacterium avium complex (MAC) is a major cause of second ary lethal infections. The only vaccine c...

Tildelt: kr 5,0 mill.

Prosjektperiode: 2007-2014

Sted: Trøndelag - Trööndelage

S-AFRIKA-Program for forskningsamarbeid med Sør- Afrika

Characterization of the Mycobacterium tuberculosis phosphorylome and its role in pathogenesis

Tuberculosis (TB) remains a major global public health concern. Approximately 2 million people die per year from TB, with South East Asia, Sub-Saharan Africa and Eastern Europe showing the highest levels of new cases and deaths. South Africa is one of the countries with the highest number of TB ...

Tildelt: kr 0,80 mill.

Prosjektperiode: 2007-2010

Sted: Vestland

S-AFRIKA-Program for forskningsamarbeid med Sør- Afrika

Nutritional intervention and novel diagnostics to improve community-based control of tuberculosis

Tuberculosis (TB) is a major public health problem in developing countries as well as in the Republic of South Africa (RSA). Despite significant strides in case detection and treatment, the prevalence of TB continues to rise at an alarming, also in the RS A. More effective diagnostic methods are ...

Tildelt: kr 0,29 mill.

Prosjektperiode: 2007-2010

Sted: Vestland

FOLKEHELSE-Folkehelse

Forskningsleder Gun Roos

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Tildelt: kr 1,0 mill.

Prosjektperiode: 2007-2010

Sted: Oslo

FOLKEHELSE-Folkehelse

Forskningsleder Siri Forsmo

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Tildelt: kr 0,89 mill.

Prosjektperiode: 2007-2011

Sted: Trøndelag - Trööndelage

GLOBHELS-Global helse

LAYVAC: Lay health worker programmes for vaccine uptake in low and middle income countries: Developing a global knowledge-base

Background: Lay health workers (LHWs), who carry out healthcare functions but have no professional healthcare qualifications, are used widely and have the potential to improve vaccination uptake in low and middle income countries (LMICs). However, data on their effects, cost-effectiveness and su...

Tildelt: kr 10,5 mill.

Prosjektperiode: 2007-2012

Sted: Oslo

GLOBHELS-Global helse

Explaining Differential Immunization Coverage: a multi-disciplinary approach

The Universal Childhood Immunization campaign has been hailed as a success story. At the UNICEF summit in 1990 it was declared that the target had been achieved. Since then, however, immunization coverage has deteriorated. But coverage is highly uneven be tween different countries and regions. In...

Tildelt: kr 0,28 mill.

Prosjektperiode: 2007-2007

Sted: Oslo

GLOBHELS-Global helse

New rotavirus vaccines: targeting childhood morbidity and mortality in low- and middle-income countries in Central Asia

The current project is aimed at reducing morbidity and mortality caused by rotavirus (RV) disease among young children in low- and middle-income countries in Central Asia. RV is the most common cause of severe acute gastroenteritis in young children and a major cause of childhood death in develo...

Tildelt: kr 8,8 mill.

Prosjektperiode: 2007-2012

Sted: Oslo

GLOBHELS-Global helse

Preparing for tuberculosis vaccine efficacy trials: Baseline epidemiology, improved diagnosis, markers of protection and phase I/II trials

This collaboration between scientists in Denmark, India, Norway, South Africa and the U. S. will conduct 3 large cohort studies of tuberculosis (TB) in Palamaner, India, using state of the art immunology to identify correlates of protective immunity and i ncipient disease. These cohorts will be a...

Tildelt: kr 18,5 mill.

Prosjektperiode: 2007-2014

Sted: Vestland

GLOBHELS-Global helse

Project establishment: Development of vaccine(s) against infections with diarrheagenic Escherichia coli and Shigella

Diarrheal diseases are the second most common cause of death in children, accounting for 1/5 of the 10.6 million annual child deaths. In addition, repeated episodes of diarrhea, especially if prolonged and associated with growth faltering, are an importan t cause of malnutrition in developing cou...

Tildelt: kr 0,30 mill.

Prosjektperiode: 2007-2007

Sted: Vestland

GLOBHELS-Global helse

Integrated Health Information Systems (HIS) for vaccination in developing countries

Improving immunisation coverage is seen as a cost effective and efficient means for improving the health of populations. However, increasing focus is being directed at populations where coverage is poor, and to populations who are marginalised and therefo re at risk. Identifying these groups is n...

Tildelt: kr 10,0 mill.

Prosjektperiode: 2007-2013

Sted: Oslo

GLOBHELS-Global helse

Novel vaccine candidates and delivery systems for HIV and influenza

Aim: We wish to generate novel vaccines for important infectious diseases such as HIV (FRIBIOMOL)and influenza (GLOBVAC). Background: Vaccination has had an enormous impact on health and longevity of humans world-wide. However, for some important diseases such as HIV, there are no available vacc...

Tildelt: kr 2,0 mill.

Prosjektperiode: 2007-2011

Sted: Oslo

GLOBHELS-Global helse

Further Developments of New Immunogenic Peptide-based HIV Vaccines Targeting Dendritic Cells

Therapeutic HIV vaccines targeting dendritic cells have so far shown more promising results than preventive HIV vaccines and may become an alternative even for prophylaxis. This Proposal describes plans for basic clinical studies on further characterizati on and developments of new immunization s...

Tildelt: kr 7,4 mill.

Prosjektperiode: 2007-2013

Sted: Oslo

GLOBHELS-Global helse

Development and validation of delivery technology for gene based prophylactic vaccines

While conventional vaccines have been instrumental in fighting a number of diseases, they have proven less successful against pathogens that require a strong cellular immune response for protection such as HIV, malaria and tuberculosis. A new and promisi ng vaccine technology is based on deliver...

Tildelt: kr 0,17 mill.

Prosjektperiode: 2006-2008

Sted: Oslo

FORM-Formidling

Formidlingsstipend for journalister og forskere 2006

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Tildelt: kr 0,11 mill.

Prosjektperiode: 2006-2007

Sted: Troms - Romsa - Tromssa

FORM-Formidling

Formidlingsstipend for journalister og forskere 2006

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Tildelt: kr 0,10 mill.

Prosjektperiode: 2006-2006

Sted: Oslo

FORM-Formidling

Formidlingsstipend for journalister og forskere 2006

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Tildelt: kr 0,10 mill.

Prosjektperiode: 2006-2006

Sted: Troms - Romsa - Tromssa

FORM-Formidling

Formidlingsstipend for journalister og forskere 2006

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Tildelt: kr 40 000

Prosjektperiode: 2006-2006

Sted: Vestland

GLOBHELS-Global helse

Pectin products from Malian medicinal plants, can they combat ailments related to the immune system?

The objective of this proposal is to identify immunological active pectin polysaccharides from Malian medicinal plants, traditionally used for wound healing and combating infections such as malaria and schistosomiasis. The use of conventional medicines is too expensive for the majority of people...

Tildelt: kr 5,3 mill.

Prosjektperiode: 2006-2011

Sted: Oslo

EVALPSYK-Evaluering - opptrappingsplan psykisk helse

Karl Erik Brofoss - Konsulentbistand for sluttrapport fra evalueringen av Opptrappingsplanen for psykisk helse

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Tildelt: kr 0,66 mill.

Prosjektperiode: 2006-2009

Sted: Oslo

EVALPSYK-Evaluering - opptrappingsplan psykisk helse

Frode Larsen - Konsulentbistand for sluttrapport fra evalueringen av Opptrappingsplanen for psykisk helse

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Tildelt: kr 1,1 mill.

Prosjektperiode: 2006-2009

Sted: Oslo

GLOBHELS-Global helse

Type 2 diabetes and lifestyle in ethnic minorities in Oslo, and in populations in Pakistan, Bangladesh and China

The global prevalence is estimated at over 143 million in 1995, 154 million in 2000 and by 2025 the diabetic population is expected to rise to 300 million, an increase of approximately 120% . Today, diabetes is a disease of the poor. We have reported an i ncreased prevalence of 400% in the urban ...

Tildelt: kr 3,4 mill.

Prosjektperiode: 2006-2010

Sted: Oslo

GLOBHELS-Global helse

Development of a subunit vaccine for prevention of reactivation of tuberculosis

Mycobacterium tuberculosis causes tuberculosis and is one of the main killers among infectious pathogens in the world, and an important factor that sustain poverty in developing countries. Applied research for development of new vaccines is therefore need ed. Transmission of tuberculosis (TB) is ...

Tildelt: kr 3,1 mill.

Prosjektperiode: 2006-2009

Sted: Vestland

GLOBHELS-Global helse

Focus on Nutrition and Child Health: Intervention Studies in Low-income Countries

Malnutrition and common infections are the leading cause of ill health and death among marginalized children who also face other health risks, such as limited health care access, poor hygiene and overcrowding. HIV infection in children directly increases their risk of common infections but adds t...

Tildelt: kr 10,9 mill.

Prosjektperiode: 2006-2013

Sted: Vestland

GLOBHELS-Global helse

Alternative Treatment Strategies in HIV Infection - research platform with integrated biological and clinical objectives

By combining complementary expertise held by our groups and collaborators both nationally and internationally, we will coordinate development of a HIV clinical platform for translational research which is particularly important in HIV infection: Relevant animal models are unavailable, studies of ...

Tildelt: kr 3,1 mill.

Prosjektperiode: 2006-2010

Sted: Ukjent Fylke

GLOBHELS-Global helse

Strengthening human resources for health. A study of health worker availability and performance in Tanzania

Shortage of health personnel and poor health worker performance are among the most pressing problems of health systems in low-income countries. This proposal represents a strategic initiative to provide evidence that will be valuable in addressing these f undamental problems. The initiative is a ...

Tildelt: kr 9,6 mill.

Prosjektperiode: 2006-2012

Sted: Vestland

GLOBHELS-Global helse

Searching for effective HIV-prevention and care in sub-Saharan Africa: focusing on local contexts

After 20 years of experience with HIV prevention, the number of people infected with HIV continues to rise, and there are still few examples of declining epidemics. Why have we not done better? This proposal is a response to the urgent need to document wh at works in community HIV prevention and ...

Tildelt: kr 10,1 mill.

Prosjektperiode: 2006-2013

Sted: Vestland

IS-BILAT-Mobilitet Norge-USA /Canada

Renal failure in ethylene glycol poisonings: The inhibitory role of oxalate crystals in mitochondrial respiratory function.

Regarding methanol versus ethylene glycol, both the toxic pathway and the treatment are very similar. Therefore, I would like to primarily focus on the mechanisms for renal toxicity, which is one of the most frequent toxic effects of ethylene glycol. Th e toxic mechanisms of ethylene glycol poi...

Tildelt: kr 78 000

Prosjektperiode: 2005-2007

Sted: Ukjent Fylke

IS-BILAT-Mobilitet Norge-USA /Canada

Understanding and prevention of unexplained stillbirths - US collaboration in the Femina study and the Norwegian Mother & Child Cohort Study

The background: Unexplained stillbirths have been the largest contributor to our perinatal mortality for decades. Women perceiving reduced fetal movements (FM) are at high risk of adverse outcomes, and are frequent and difficult challenges in obstetric c are. There are no evidence-based protocol...

Tildelt: kr 0,27 mill.

Prosjektperiode: 2005-2007

Sted: Oslo

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