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Limb wounds in horses are common, however healing is exceedingly slow and fraught with complications. Contrary to body wounds, limb wounds demonstrate only a small amount of wound contraction. The specialist procedure of applying split-thickness skin grafts to limb wounds stimulates wound contraction by unknown mechanisms. The objective of this project is to identify those mechanisms to develop a treatment strategy for equine limb wounds for use in general  practice. Limb wounds are severely impacting animal welfare due to an extended healing/treatment duration, and the risk of euthanasia due to a poor functional outcome. By stimulating wound contraction, healing time will be reduced, and the functional outcome improved, directly benefitting the welfare of wounded horse and reducing treatment cost for the owner. Aim: To identify dermal components stimulating wound contraction, and to develop this knowledge into future state-of-the-art treatment of equine limb wounds for use in general practice. Hypotheses: i) Application of dermal fractions to collagen gels seeded with equine fibroblasts will increase gel contraction in vitro; ii) Application of dermal fractions to experimental limb wounds in vivo, will increase wound contraction resulting in a faster healing time versus wounds treated by conventional methods. Methods: i) The contractile effect of different dermal components will be assessed in a collagen gel/ fibroblast model; ii) Identified dermal components will be tested in a standardized experimental limb wound model in vivo (n=5). Ultimately, results from this project are expected to improve wound treatment in horses, directly impacting animal welfare by reducing healing time and improving the functional outcome of wounded horses. This will also directly benefit horse owners and caretakers and making veterinarians able to offer better treatment solutions.

HESTEFORSK - Raskere og bedre sårheling hos hest med autologe hudkomponenter

Effektene av fysisk og seksuell vold på ofre og deres familier kan være ødeleggende og vedvarende, med potensielt langvarige konsekvenser for fysisk og mental helse, utdanning, sysselsetting og bruk av velferdstjenester. Mens strafferettssystemet anses som en viktig del av offerets gjenopprettingsprosess, er det begrenset empirisk forskning på hvorvidt strafferettslige prosesser hjelper og/eller hindrer bedring langs disse ulike dimensjonene. I dette prosjektet vil vi adressere dette kunnskapshullet ved å bruke en kombinasjon av kvantitative og kvalitative forskningsmetoder. I de kvantitative analysene vil vi bruke administrative registerdata som dekker hele befolkningen sammen med kvasi-eksperimentelle metoder for å kunne trekke kausale slutninger. Vi vil også benytte maskinlæringsteknikker for prediksjon. De kvalitative analysene vil supplere de kvantitative analysene ved å gi kontekst til et komplekst felt av saker og ofre og ved å identifisere potensielle mekanismer mellom strafferettslige prosesser og utfall for ofrene. Samlet vil disse metodene gi en mer robust, representativ og nyansert forståelse av hvordan kontakt med strafferettssystemet påvirker offeret på tvers av flere viktige livsområder både på kort og lang sikt. Prosjektet ledes av Folkehelseinstituttet (FHI) med Frischsenteret og Universitetet i Oslo som partnere. Prosjektet har et rådgivende utvalg med medlemmer fra Nasjonalt kunnskapssenter om vold og traumatisk stress (NKVTS), ETH Zurich, Universitetet i Oslo, Frischsenteret, Universitetet i Bergen, og OsloMet. Det er også tilknyttet en brukergruppe bestående av personer og organisasjoner som er i kontakt med ofre for vold og overgrep.

Victims of sexual and physical violence is one of the most vulnerable groups in our society. The criminal justice system (CJS) serves a critical role in providing assistance to victims of these crimes, enabling them to seek justice, protection, compensation, and closure. Yet, knowledge about whether the CJS helps or harms these victims is extremely limited. This project aims to remedy this by providing a comprehensive understanding of the role of the CJS in supporting and providing restoration for victims of physical and sexual violence in Norway. We will utilize a combination of quantitative and qualitative research methods across disciplines to study outcomes across multiple important life domains, both in the short and long run. For the quantitative analyses we will use exceptionally rich longitudinal administrative register data with full population coverage combined with state-of-the-art quasi-experimental methods for credible causal inference and predictive machine learning techniques. The qualitative analysis will be based on narrative interviews with victims, providing context and insights into how interactions with the CJS shape life stories. The results will yield a robust and nuanced understanding of how the different stages of the CJS impacts victims. This is particularly urgent given how the current emphasis on legal responses to assaults has caused a sense of obligation and civic duty for especially women to report incidents, while the chances of legal closure remain small. In addition to advancing the methods for quasi-experimental designs and machine learning within quantitative criminology, this project will provide valuable insights for policymakers, stakeholders, and practitioners working in the field of victim support and rehabilitation and may inform current legal reform efforts aimed at addressing these issues.

Helpful or harmful: The effects of criminal justice system contact on victims of sexual and physical violence

Hovedmålet med kreftbehandling er å eliminere kreftceller og dette er tradisjonelt oppnådd ved kirurgi, bruk av giftige medikamenter (cellegift) og stråling. En ny og betydningsfull tilnærming til kreftbehandling kalt immunterapi, har derimot fått mye oppmerksomhet det siste tiåret; Her forsøker leger og forskere å utnytte immunsystemet vårt for å målrettet  ødelegge kreftceller. En nøkkelaktør i denne banebrytende tilnærmingen er en gruppe «drapsmenn» i immunsystemet kjent som cytotoxiske T-lymfocytter (CTL-er). Disse cellene har en bemerkelsesverdig evne til å oppdage kreftceller ved å gjenkjenne unormale molekyler på overflaten av kreftcellene - molekyler som friske celler ikke har. Når CTL-er gjenkjenner kreftcellene ødelegger de dem ved å frigjøre giftige molekyler som initierer kreftcellenes selvdestruksjon. 
 
Selv om betydelige innsats har blitt dedikert til å forstå hvordan CTL-er aktiveres og hvordan de gjenkjenner kreftceller, vet vi mindre om de påfølgende hendelsene inne i kreftcellene som fører til deres død. Fra før vet vi at CTL-er kan initiere to forskjellige typer celledød i kreft: den første, kalt apoptose, er en stille og ordnet prosess der kreftcellene krymper og brytes opp uten å varsle immunsystemet; den andre, kalt pyroptose, er en mer dramatisk prosess som involverer dannelse av åpninger i cellemembranen, noe som fører til at cellene svulmer opp og sprekker. Under denne cellebristen blir innholdet inne i cellene frigitt i omgivelsene, og dette kan fungere som 'faretegn' som kan stimulere en sterkere immunrespons mot kreftcellene. Betydningen av denne cellebristen for å forsterke anti-tumorresponsene vil bli undersøkt i dette prosjektet. 
 
Videre er vi fascinert av muligheten for å avdekke ytterligere, ennå ukjente, former for celledød indusert av CTL-er. Utforsking av disse dødsrelaterte prosessene i kreftcellene kan potensielt øke effektiviteten av immunterapi og bidra betydelig i den pågående kampen mot kreft.

The primary goal of most cancer therapies is to induce cancer cell death. Immunotherapy relies on the cytotoxic activity of lymphocytes such as natural killer cells (NKs) and cytotoxic T lymphocytes (CTLs) to achieve this. While a significant amount of research in immunotherapy focuses on the events within cytotoxic lymphocytes or at the interface between cytotoxic lymphocytes and cancer cells, less is known about the molecular mechanisms that orchestrate cancer cell death, particularly in the case of CTL-mediated death.
CTLs are known to induce two types of cell death in cancer: non-inflammatory apoptosis and proinflammatory pyroptosis. Pyroptotic cancer cells release proinflammatory signals that attract immune cells to the tumor site, thereby enhancing the anti-tumor response. Cell lysis is a common outcome of pyroptotic cell death. It is unclear whether lysis can be decoupled from pyroptosis in cancer cells and whether the proinflammatory properties of pyroptotic cancer cell death depend on lysis. Moreover, it remains unknown whether CTLs can induce other forms of cell death in cancer, apart from apoptosis and pyroptosis.
Studying the mechanisms of CTL-mediated cancer cell death is challenging because CTLs selectively target cells expressing specific antigens. However, given the critical role of CTLs in immunotherapy, it is essential to deepen our understanding of CTL-induced cancer cell death.
This project aims to develop novel methodologies to investigate the death mechanisms that are initiated by CTLs. In addition, we will identify new pathways and mediators involved in CTL-induced cancer cell death. Furthermore, we will assess the contribution of proinflammatory cell death and lysis in promoting anti-tumor responses in vivo. Overall, this research will improve our knowledge of the molecular mechanisms of CTL-mediated cancer cell death and potentially reveal novel targets to enhance the efficacy of cancer immunotherapy.

T-cell-mediated proinflammatory cell death and lysis in cancer

The high seas are those marine areas under no State's jurisdiction. So far, all marine renewable energy (RE) activity is being conducted under State's jurisdiction. However, recent advances in technology are raising the prospect of carrying out RE activity on the high seas. Currently, only seabed mining activities in the Area have been regulated. The Area is the seabed and ocean floor beyond the limits of State's jurisdiction. From the legal viewpoint, the main gap is a lack of an international regulatory framework, informed by participatory mechanisms and supported by scientific evidence, for RE activities on the high seas, especially regarding their environmental and social impacts. 
The primary project objective (O) is to provide the scientific community and policymakers with science-informed and indigenous knowledge-based recommendations in support of the development of  RE regulation on the high seas. 
Two specific Os are set to complement the primary O, namely:
O1 To advance the use of systematic consultation processes that facilitates research at the crossroads of marine sciences and law. 
O2 To advance critical knowledge and understanding of environmental pressing issues comparable to the regulation of RE on the high seas, such as deep-sea mining in the Area.
A multistep innovative methodology will be adopted, by integrating marine scientific knowledge, consultative processes, and advanced critical research in the subject matter. A case study (interdisciplinary and participatory) involving marine scientists, indigenous and coastal communities and policy makers will be conducted onboard the Research Vessel KronPrins Haakon at the beginning of the project. The case study outcomes will be analysed through critical legal analysis to build a knowledge base for policy recommendations. 
The project will advance the PI’s career in an international research environment, allowing her to generate independent, high-quality, and reproducible results.




Renewable energy on the high seas – science-informed and indigenous knowledge-based recommendations for regulatory and governance challenges

The Arctic region is witnessing more frequent shipping accidents than ever which require accurate search and rescue operations. The existing communication systems use drones with radio frequency (RF) technology, which has limited bandwidth and cannot offer 4G/5G connectivity due to harsh weather constraints. It further limits the capacity of drones and affects the resolution of images and videos. The current research proposes to design free space optical communication (FSOC) link-based drones that can enhance connectivity between multiple drones and rescue ships as well as the capacity of drones to produce high resolution images and videos. The proposed FSOC-based drones can provide highspeed connectivity than the existing RF technology. The research will collect atmospheric turbulences data from the Arctic region and use it for designing the FSOC link. Furthermore, to enhance the capacity of FSOC-based drones, the research will design advanced multiplexing schemes (Mode Division Multiplexing and Orthogonal Code Division Multiple Access) and to ensure link stability, omnidirectional receiver will be designed. The research will further evaluate the performance of proposed FSOC link under the impact of various atmospheric turbulences. The expected outcomes of this research will lead to the optimisation of FSOC-based drones in expanding search areas and improving communication systems for SAR operations in the Arctic region.

Optimization of Free Space Optical Communication Link based Drones for Search and Rescue Operations in the Arctic Region

Dette prosjektet, kalt Hukommelse for musikk, fokuserer på det økende antallet mennesker over hele verden som lever med demens, spesielt Alzheimer's sykdom (AD). AD starter typisk med hukommelsesproblemer og påvirker etter hvert daglige aktiviteter. Aktive musikkintervensjoner, spesielt sang, har vist positive effekter på humør, atferd og livskvalitet for personer med demens, men deres innvirkning på kognisjon er ikke godt forstått. Prosjektet har som mål å fylle dette kunnskapsgapet ved å studere effektene av å lære nye sanger på kognitiv, atferdsmessig og hjernemessig funksjon.

Studien vil omfatte hjemmeboende voksne over 65 år med AD fra Argentina, Østerrike og Norge. Deltakerne vil gjennomgå 5 måneder med intensiv musikalsk opplæring (to ganger i uken) og 5 måneder med minimal opplæring (en gang i måneden) i tilfeldig rekkefølge, med en to måneders pause imellom. Intervensjonene inkluderer å lære nye sanger med en personlig musikklærer. Generell kognisjon vil bli målt ved bruk av Alzheimer's Disease Assessment Scale - Cognitive (ADAS-cog), og hukommelse for musikk vil bli vurdert gjennom ulike metoder, inkludert atferdsoppgaver og hjerneaktivitet (EEG). Humør vil også bli evaluert i hver økt.

Målet er å inkludere 113 deltakere for å sikre pålitelig påvisning av meningsfulle effekter. Studien vil utforske hvordan humør og hukommelse for musikk bidrar til endringer i kognitive evner, og om disse effektene varierer basert på faktorer som kjønn, alder, AD-stadium, eller tidligere musikalsk opplæring og generell utdanning. Prosjektet vektlegger samarbeid mellom forskere, tjenesteytere og brukere for å sikre studiens relevans og anvendelighet.

The number of people living with dementia is increasing and is high in low, middle, and high-income countries. Alzheimer’s disease (AD), the most common type of dementia, manifests itself initially with cognitive impairment in memory domains, and later affects all activities of daily living. Active music interventions, particularly singing, can help to improve mood, behaviour problems, and quality of life. Too little is known about their effects on cognition, although some promising studies exist. The M4M project aims to fill this gap by measuring effects of learning new songs on clinical, behavioural and brain functioning. Specifically, M4M aims to examine changes in general cognitive functioning and memory for music in non-musician adults with AD undergoing intensive individual musical training based on singing novel songs, compared to minimal training.
        Home-dwelling adults with AD, 65 years or older, in 3 countries (Argentina, Austria, Norway), will receive 5 months of intensive intervention (2x/week) and 5 months of minimal intervention (1x/month), in random order, with a 2-month break in between. Interventions will entail learning new songs with an individual music teacher. At the end of each intervention period, general cognition will be measured with the Alzheimer's Disease Assessment Scale – Cognitive (ADAS-cog) by a person who is unaware of the intervention received. Memory for music will be tested with observations, behavioural tasks, and brain responses (EEG). Mood will be assessed in each session. We aim to include 113 participants; this will help us to reliably detect clinically meaningful effects. We will also examine how mood and memory for music lead to changes in cognitive abilities, and whether effects depend on sex, age, AD stage, or previous musical training or general education. M4M will be conducted in close collaboration between academic researchers, service providers, and service users to ensure relevance and applicability.

Memory for Music: Effects of individual intensive musical training based on singing in non-musicians with Alzheimer’s disease

Currently, 28.2% of the total EU-28 greenhouse gas emissions come from the power sector, a large contributor to greenhouse gas emissions. Consequently, the emphasis of the research in power generation has swung towards assessing highly efficient and greener power cycles. In this reference, the novel supercritical carbon dioxide Brayton cycle (sCO2-BC) is an ideal choice that outstrips other formally well-known power cycles (Brayton & Rankine cycles). In sCO2-BC, the role of the pre-cooler is critical. It serves as a sink to the power cycle and regulates the conditions at the compressor's inlet. The compressor's inlet temperature is intended to be maintained close to the critical temperature of carbon dioxide (CO2) to achieve greater cycle efficiencies. However, exceptionally higher values of the specific heat capacity of CO2 near its critical point (up to 40 times higher than water) require exceedingly high water flow rates on the cold side to achieve the desired exit temperatures of CO2. Consequently, the pre-cooler's pumping power requirements become high enough to deteriorate the cycle's performance. This problem can only be mitigated by exploring new channel geometries with enhanced thermohydraulic characteristics. Therefore, the proposed study plan to characterize the complex thermohydraulic characteristics in the pseudocritical region of CO2 using a multifaceted technique that includes, experimental, numerical, and machine learning techniques. The proposed work will provide a step forward to the success of sCO2-BC technologies that, in turn, will facilitate its integration with the green energy resources (generation-IV nuclear reactors and solar concentrated plants), helping to meet the EU's 2030 climate and energy framework goals of achieving at least 32% share for renewable energy.

Evaluation of thermohydraulic characteristic of printed circuit heat exchangers in pseudocritical region for supercritical CO2 cycle

Norge har under Parisavtalen påtatt seg en forpliktelse til å redusere klimautslippene sine med minst 55 prosent innen 2030 sammenlignet med nivået i 1990. Hittil har vi kun oppnådd 5 prosent av dette målet; vi har følgelig kun syv år på å redusere de resterende 50 prosent for å imøtekomme målene. For 2050 har vi satt oss enda større mål: å redusere klimautslippene med hele 90 prosent. Bakgrunnen for målene er at vi prøver å unngå de verste scenarioene FNs klimautvalg skisserer opp i sine rapporter. I tillegg har energiforbruket økt, og prognosene fra Statnett for ulike scenarier viser at energiforbruket skal fortsette å øke. Vi trenger følgelig mer energi. Dette har bidrat til at diskusjoner rundt kjernekraft i Norge er høyaktuelle og pågående. Norsk Kjernekraft AS har blitt opprettet med formål om å bygge Norges første kjernekraftverk. I tillegg ble det i fjor også bevilget 200 millioner kroner fra Regjeringen til et nytt senter som skal drive med nukleær forskning. Målet er å styrke den norske kunnskapsberedskapen på det nukleære området. Dette betyr at vi beveger oss i en retning hvor kjernekraft en dag kan bli aktuelt i Norge, og noen mener at dette er den eneste veien å gå hvis vi skal nå målene våre for 2050. Men i dag sitter vi med flere spørsmål enn svar, blant annet: Hvilken teknologi og leverandør burde vi velge? Er regelverket for snevert og strengt? Hvordan kan dette gjøres og samtidig ivareta sikkerhet? Hvordan tjener et kjernekraftverk penger?

Dette prosjektet skal svare på samtlige av disse spørsmålene i en detaljert og omfattende analyse. Her bruker vi grunnlagsdata til å vurdere dagens forskning opp mot hvordan industrien i andre land opererer, og ut ifra dette forsøke estimere hva risikoen knyttet til å bygge kjernekraft som industri i Norge er. Prosjektet sikter på å gi et så helhetlig bilde som mulig slik at vi kan gjøre oss opp en mening basert på fakta; om kjernekraft passer inn i miksen av det som utgjør norsk energi.

Denne prosjektbeskrivelsen skisserer forskningen Vala Maria Valsdottir (omtales herunder som stipendiaten) skal utføre innenfor sin doktorgradsavhandling. Prosjektet skal være en del av Senter for nukleær forskning (SNF) som fikk midler vinteren 2023.
Ph.d.-prosjektet er initiert av Inmeta Consulting AS, som igjennom denne ph.d.-stillingen vil bli en del av SNF. Inmeta planlegger en prosjektperiode på fire år, hvor stipendiaten arbeider 75 % med ph.d.-prosjektet og 25 % med vanlig virksomhet hos Inmeta. 
Prosjektet skal undersøke muligheten for kjernekraft som industri i Norge. Dette er både en samfunnsaktuell problemstilling samt en som medlemmene i SNF er interessert i å utforske. Stipendiaten kommer derfor til å samarbeide med alle aktørene som er involvert i senteret og benytte forskningsdata fra dem. Dette gjelder da spesielt Institutt for energiteknikk (IFE) som har mest grunnlagsdata som er relevant for dette prosjektet.
Kandidaten ferdigstilte en masteroppgave høsten 2020 i kjernefysikk på Universitetet i Oslo (UiO) og har derfor gode og relevante grunnkunnskaper for å ta på seg et slikt prosjekt. I tillegg har kandidaten tre års erfaring innenfor energibransjen, og er derfor oppdatert på industrien og forstår deres problemstillinger godt.

Er kjernekraft aktuelt for Norge?

Potetskrell, et biprodukt fra industriproduksjon av potet (pommes frites, flak, chips mm.) er en råstoff ressurs som kan bli bedre utnyttet til nye formål. Skrellet er nemlig en rik kilde på antioksidanter, stoffer som planter naturlig har i seg for å beskytte mot skadelige UV-stråler og reaktive forbindelser som oksygen radikaler. Antioksidanter behøver vi også å tilsette i matvarer for å beskytte og ta vare på umettet fett så det ikke blir harskt og vondt i kontakt med luft. I dag brukes flere ulike syntetiske stoffer i matvarer for å hindre oksidasjon av fett og oljer. Men det er reist bekymring rundt sikkerheten for bruken av dem. Matvareindustrien, myndigheter og forbruker ønsker derfor å fjerne flere syntetiske antioksidanter og erstatte dem med naturlig alternativer. Det er imidlertid svært få slike produkter som er godkjent og tilgjengelig på markedet. Prosjektet Peel Preserve, som har et klart bærekraft mål, skal vise om et uttrekk av antioksidanter laget på industrielt potetskrell råstoff kan fungere som konserveringsmiddel og erstatte noen av de stoffene som brukes i dag. Tre næringsmiddelbedrifter skal teste potetskrell-ekstraktet i noen av sine produkter og utføre både interne og eksterne analyser på effekten. Men en viktig forutsetning for at potetantioksidant kan tas i bruk som nytt tilsetningsstoff i mat er at det blir godkjent av den Europeiske matsikkerhets myndigheten (EFSA) og gitt et E-nummer. Prosjektet skal igangsette denne lengre flertrinns godkjennings prosessen. Parallelt skal det utvikles en forretningsmodell og nødvendig beskyttelse rundt teknologien. Dersom industrien etter testingen av potetantioksidanten, vurderer denne som er god erstatning til konkurransedyktig pris, og en EFSA-godkjenning kan oppnås på sikt, åpner det for å kommersialisere et naturlig plante-basert produkt til beste for forbruker og for miljøet. Bak prosjektet Peel Preserve står Høgskolen i Innlandet i samarbeid med Nofima og Klosser Innovasjon.

Preserving foods with potato peels: Industry-relevant validation and first regulatory assessment of a new natural antioxidant

Applied Biocatalysis is the development through science and engineering of useful biological catalysts and their commercial applications. The BNCM 2024 conference has an intention to gather approx. 100 international and national scientists from academia and industry in addition to PhD students from the international community. BNCM 2024 will be the 7th in this series of meetings with attendees from both academia and industry presenting and discussing the newest research in enzyme catalysed reactions in other media than water. The conference series was started in 1986 by professors Hans Tramper and Urs von Stockar, University of Wageningen, the Netherlands, and has later been chaired in Russia, Italy and Germany before Elisabeth Jacobsen at NTNU was give the honor of chairing the conference.  Collaboration in biocatalysis research has been supported by EU Frameworks as three subsequent COST actions. The first action, COST Action D25 "Applied Biocatalysis. Stereoselective and environmentally friendly reactions catalysed by enzymes " (2001-2007) was initiated and chaired by professor Thorleif Anthonsen, NTNU, the founder of the Biocatalysis Group at NTNU, which the project leader of this conference now chair. The strategy of applied biocatalysis fits well under the definitions of white biotechnology and Sustainable chemistry (Suschem) and fits also well with the EU Green Deal Strategy.

7th International Conference on Biocatalysis in Non-Conventional Media

Midlene fra MCA-3.01 Marie Curie Actions fordelt på år

Midlene fra MCA-3.01 Marie Curie Actions fordelt på fylker

Midlene fra MCA-3.01 Marie Curie Actions fordelt på fagområde

Rheumatoid Arthritis and Periodontal Inflammatory Disease (RAPID)

Eranet Sustainable Urbanisation Global Initiative

Cities around the globe are struggling to meet the needs of their citizens with respect to food, energy and water. These three sectors are inextricably linked and actions in one sector more often have impacts in one or both of the others; these interacting sectors can therefore be seen as a Food-Energy-Water Nexus (FEW Nexus) of systems.   The ERANET Sustainable Urbanisation Global Initiative (EN-SUGI) will bring  together the fragmented research and innovation expertise across Europe and beyond to find innovative new solutions to this FEW Nexus challenge. Furthermore, by linking the activity of the Joint Programming Initiative (JPI) Urban Europe and the Belmont Forum (BF), EN-SUGI develops more resilient, applied urban solutions that bring research and innovation together from across the globe.  EN-SUGI is a project that foresees the participation of 19 Funding Agencies eligible for the EU top up, 18 from JPI Urban Europe and 1 from Argentina, and 6 FAs non eligible for EU top up, under the umbrella of the Belmont forum , collaborating on a volunteer base.  EN-SUGI Main objectives and impacts are: To support development of practical innovations and new collaborative research that will allow urban areas to understand and address the challenges of the Food-Energy-Water systems. (Impact = 12-14 projects funded, and 15 cities/local authorities engaged) To provide a framework for aligning R&I agendas of JPI Urban Europe and the BF,. The alignment will help foster transdisciplinary collaboration and co-creation in research and innovation, and facilitate the use of global expertise and knowledge (Impact = 24 funding organisations involved) EN-SUGI will foster development of international relationships between the different parts of the research and innovation community – to enable them to contribute to addressing those challenges and goals, while aligning them to wider, strategic initiatives, including the SRIA agenda, Future Earth and UN –Habitat.

Coordination of European Transnational Research in Organic Food and Farming Systems Cofund

Organic agriculture is considered to be one of the important development pathways towards a more sustainable agriculture and food production. This development has been and will be dependent on continuous research and innovation. CORE Organic started in 2004 and has been evolving for more than a decade. The present proposal for a CORE Organic Cofund will continue, to update and consolidate the series of transnational research calls that support a focused and coordinated research and innovation effort covering the most important challenges along the organic value chains, for example: increasing the organic production potentials, enhancing resource efficiency, and improving animal welfare. In addition this research and innovation plays a key role in adapting to the new EU regulations on Organic Farming. The new CORE Organic network will be expanded with additional partners from Netherlands and Italy totalling to 25 partners from 19 countries. One joint call with 3-4 topics will be launched with co-funding from the European Commission and another call without EU co-funding is being planned for 2019 as part of the additional activities. Other ERA-NETs with a similar scope will be invited to join this second call.  The CORE Organic partners are working to increase innovation potential, knowledge accessibility, alignment of national research and international outreach in support of the ERA-NET’s objectives. CORE Organic will closely monitor the funded projects and offer assistance regarding stakeholder involvement and dissemination in order to secure high impact of the research efforts. An impact assessment will be performed after the end of the projects. Looking to the future, the CORE Organic Cofund aims to deliver results that can be used to develop the organic sector throughout Europe and the world, and to continue to be a key player in the European Research Area.  

Maritime and Marine Technologies for a New ERA

The overall goal of the proposed Cofund is to strengthen the European Research Area (ERA) in maritime and marine technologies and Blue Growth. The realisation of a European research and innovation agenda needs a broad and systematic cooperation in all areas of waterborne transport, offshore activity, marine resources, maritime security, biotechnologies, desalination, offshore oil & gas, fisheries, aquaculture etc. covering all relevant maritime and marine sectors and regions for a sustainable development of the maritime sector. Research and innovation activities in these fields cannot be tackled either at national levels alone, or solely by a single sector. Coordinated actions are required for the maritime industry to strengthen Europe’s position in this important and complex economic field in a global market. The proposing consortium will organise and co-fund, together with the EU, a joint call for trans-national research projects on different thematic areas of Blue Growth. Furthermore, additional joint activities that go beyond this co-funded call are planned, in order to contribute to the national priorities as well as to the Strategic Research Agenda of JPI Oceans and WATERBORNE. With the cooperation of ERA-NET MARTEC and JPI Oceans, a broader variety of topics with a larger amount of funding will be available for the trans-national projects. Moreover, the focus of development in MarTERA is given to technologies (instead of sectors) due to their potentially large impact to a wide range of application fields. The proposal responds to the topic ERA-NET Cofund on marine technologies of the work programme 2016-2017 of the societal challenge 2 (Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bio-economy) under Horizon 2020. Thereby it also contributes to the overall EU objective of building the ERA through enhanced cooperation and coordination of national research programmes. 

Transfer of Organisational innovations for Resilient, Effective, equitable, Accessible, sustainable and Comprehnsive Health Services and Systems.   

In order to strengthen the sustainability and resilience of health services and systems a unique consortium of governmental and funding organizations plus research institutes, has expressed the ambition to systematically learn from the organisation of care in other settings. Overall objective of TO-REACH is to provide groundwork for a future joint research programme that will contribute to the resilience, effectiveness, equity, accessibility and comprehensiveness of health services and systems. We will do so along two work streams: A) We will develop a research program on cross-border learning from good (or even innovative) models of care and the conditions needed to transfer them to other settings for implementation. It could refer to anywhere in the care chain depending on the priorities as identified in a Strategic Research Agenda (SRA) within this project. Conceptual, methodological and empirical advancement will be achieved through 4 meta-questions that will instruct research under a future joint research programme, linking to what counts as good models of care, what are the conditions required for transferability, what are the conditions for up-scaling, and how do they contribute to the performance of health care organisations and systems. B) We will build a platform for funding organizations that allows for collaboration and coordination in the project and projected joint research programme. This will synchronize priorities and activities, hence improving the quality and applicability of research with a focus on the topic areas as described under A. TO-REACH will pursue five specific objectives: Mapping health system challenges and priorities by synthesizing different materials and stakeholder inputs; Developing a framework and providing a knowledge synthesis on the above-mentioned meta-questions; Establishing sustainable cooperation of research funding bodies and links with other initiatives; Developing a SRA through agenda setting at European and Member State level; Disseminating the results of TO-REACH. 

Existing and rising inequalities pose fundamental challenges to European societies and economies. Large disparities in human and social capacities are counterproductive to a sustainable and creative economy and participatory governance and inclusion. The increasing gulf between rich and poor, exacerbated by the recent financial and economic crises, is a key concern. The sources of inequalities in contemporary societies are complex and highly intertwined and they and their consequences can only be understood through comprehensive, comparative and innovative research activities.   It is for this reason that the NORFACE Network is committed to launch a transnational research programme on the topic of Dynamics of Inequality Across the Life-course: structures and processes (DIAL). The DIAL programme will contribute to understanding the dynamics of inequalities as they unfold over the life-course, causal processes and drivers in relation to these inequalities, the role of time with regard to inequalities and the impact of these inequalities on social cohesion. The specific challenge of this Call is to address the dynamics comparatively in their social, cultural, economic and political dimensions and to disentangle the impact of past events and current circumstances on later outcomes to provide solutions to reverse inequalities across the life-course.  The NORFACE DIAL programme will coordinate the research efforts of the participating European Member States by implementing a joint trans-national call with European Commission co-funding to fund innovative comparative, transnational and interdisciplinary research initiatives within this thematic field. The NORFACE Network has received core funding under the European Union’s ERA-Net scheme since 2004 and has developed a close partnership of European national agencies responsible for funding research activities in the social sciences. The DIAL programme builds on the successes of the NORFACE Network. 

Dynamics of Inequality Across the Life-Course: structures and processes

QuantERA ERA-NET Cofund in Quantum Technologies Quantum Technologies (QT) has become a new and fast developing area of research initiated by a realisation that quantum physics opens up radically new modes of quantum information processing and communication. European researchers have been at the forefront of these developments delivering many groundbreaking scientific results and advancing technological exploitation. The need to reinforce European excellence in QT and the highly interdisciplinary nature of QT call out for an integrated Europe-wide approach to support research efforts in this area. The central objective of the QuantERA Programme involving 31 agencies is to launch a transnational Co-funded Call that will cover 26 countries. The planned budget of this funding opportunity amounts to  25 590 000 EUR of national contributions. It is expected that the EC will allocate an additional EUR 11.5 million to the Co-funded Call budget and other project tasks. Launching a Co-funded Call will be complemented by a range of additional activities aimed at stimulating cooperation within the research community, creating and maintaining links between academia and industry, building a toolkit on responsible research and innovation in QT, exchanging best practices, and engaging in a dialogue with policy makers about the design of future funding instruments. The QuantERA proposal conforms to the specific challenges and scope of the Work Programme Horizon 2020-Future and Emerging Technologies for 2016-2017 by providing a structured framework to coordinate national and regional research programmes in the QT. In accordance with the Work Programme, the scientific scope of the QuantERA Call will focus on new technologies facilitated by specific quantum phenomena such as superposition states, the no cloning rule, or entanglement to achieve new or radically enhanced functionalities.  

QuantERA ERA-NET Cofund in Quantum Technologies

Nanomedicine is the application of nanotechnology to medicine and healthcare. The field takes advantage of the physical, chemical and biological properties of materials at the nanometer scale to be used for a better understanding of the biological mechanisms of diseases at the molecular level, leading to new targets for earlier and more precise diagnostics and therapeutics. Nanomedicine, rated among the six most promising Key Enabling Technologies, is one of the most important emerging areas of health research expected to contribute to one of the strategic challenges that Europe has to face in the future: Provide effective and affordable health care and assure the wellbeing of an increasingly aged population.  EuroNanoMed III (ENM III) builds on the foundations of ENM I & II, which launched 7 successful joint calls for proposals since 2009, funded 51 transnational research projects involving 269 partners from 25 countries/regions, and allocated € 45,5 million to research projects from ENM funding agencies. ENM III consortium, reinforced with 12 new partners  from Europe, Canada and Taiwan, is committed to fostering the competiveness of European nanomedicine actors taking into account recent changes in the landscape and new stakeholders and challenges, as identified in the SRIA in nanomedicine. The first joint call for proposals will be co-funded by ENM III partners and the EC. After the co-funded call, three additional joint transnational calls will be organized and strategic activities will be accomplished in collaboration with key initiatives in the field. ENM III actions focus on translatability of project results to clinical and industry needs.      

ERA-NET ON NANOMEDICINE

Europe is facing major economic challenges that require an ambitious economic policy for the 21st century. The EU has set out its vision for Europe's social market economy in the Europe 2020 strategy, which aims at confronting our structural weaknesses through progress in three mutually reinforcing priorities : • smart growth, based on knowledge and innovation, • sustainable growth, promoting a more resource efficient, greener and competitive economy, • inclusive growth, fostering a high employment economy delivering economic, social and territorial cohesion. MANUNET III, as a continuation of MANUNET II, is aligned with the European priorities and pretends to create a smart sustainable growth in the European manufacturing sector by coordinating the research and innovation efforts in the field of advanced manufacturing with a special focus in the key areas of new production processes, adaptive manufacturing systems and technologies for the factory of the future. The project will also reinforce the territorial cohesion through an extended collaboration network. The consortium pretends to respond to the actual economic crisis by promoting the transnational research, innovation and entrepreneurship in the industrial sector, especially in the SMEs, which are the backbone of Europe's economy. Through this strategic and integrated approach to innovation in advanced manufacturing, MANUNET III pretends to maximise European, national and regional research and innovation potential.

ERA-NET ON ADVANCED MANUFACTURING TECHNOLOGIES

The main objective of this action is to empower the network of National Contact Points (NCP) for Small medium-sized enterprises - SMEs and Access to risk finance (SMEs, ARF) under Horizon2020, by promoting a systemic service and knowledge provider for SMEs, industry and ARF community. Such knowledge and service provider will include collaboration and networking with relevant networks in thematic areas across the three Pillars of Horizon 2020, as well as networks focusing on SMEs such as the Enterprise Europe Network - EEN. Special attention will be dedicated to strengthening the knowledge of less experienced NCPs from Member States (MS) and Associated Countries (AC) in order to deliver professional cross borders know-how including the EU, National and regional level The Network will address the real needs of European SMEs and industry, notably newcomers , established in the MS and AC with a view on  stimulating, encouraging and facilitating a more effective participation of European companies into the several funding opportunities included in Horizon 2020. 

Access to Risk Finance and SMEs NCP cooperation network

The JPI for Urban Europe ERA-NET co-fund Smart Urban Futures (ENSUF) objectives are: - To tackle fragmentation and the implementation gap.  - To contribute to integrated sustainable urban development.  - To strengthen European urban research and innovation alignment.  - To scale up and translate best practices.  - To develop, analyse and test new strategies and technologies of urban governance and urban living in order to shape the economic, social and environmental needs of citizens for sustainable urban development.  ENSUF will call for transnational research and innovation projects that operationalise and translate a framework of three main elements, and launch the Urban Europe response to the implementation gap in sustainable urban development. The three main elements are:  - Transdiciplinary co-creation in research and innovation.  - Smart integrated urban development.  - Utilizing the spatial dimensions and processes of urban areas.   These three elements will be integrated by transnational, forward-looking and comparative research and innovation projects focused on the following three priority call topics:  - Concepts and strategies for smart urban transformation, growth and shrinkage - New dynamics of public services - Inclusive, vibrant and accessible urban communities  The ENSUF Cofund proposal responds to the Horizon 2020 work programme for 2014 call ‘EURO-5-2015: ERA–NET on Smart Urban Futures, Overcoming the Crisis: New Ideas, Strategies and Governance Structures for Europe’. The EURO-5 call scope is to analyse strengths and weaknesses of current models of urban development, in order to improve knowledge and to identify and shape urban needs. In response, ENSUF will deliver (a) knowledge (strengths and weaknesses of urban development); (b) methodologies (new methods, tools and network approaches) and (c) a validation/assessment of the co-creation model and (d) outline new pathways for urban development. 

ERA-NET Cofund Smart Urban Futures

The aim of the ERA-GAS Cofund is to strengthen the transnational coordination of research programmes and provide added value to research and innovation on greenhouse gas (GHG) mitigation in the European Research Area.  ERA-GAS will organise a single joint transnational call for proposals with cofunding from the European Commission (EC).  In addition, ERA-GAS will undertake additional joint activities including at least one other joint call without EC cofunding.  By pooling national money and funding projects at a European/international level, ERA-GAS will achieve a critical mass for funding GHG research, thereby reducing duplication, harmonising research effort and making more efficient use of limited resources. Greater cooperation will enhance innovation capacity in the European Research Area and encourage the development of enabling solutions to reduce GHG emissions and improve inventories. ERA-GAS will work closely with other ERA-NETs and reinforce existing collaborations between actors in the research area (e.g. via FACCE-JPI and the GRA). A plan will also be drawn up for future collaborative actions to ensure that enhanced cooperation will be maintained past the lifetime of the ERA-NET. Through collaboration in this ERA-NET and additional joint activities, partners in the consortium will exchange experience and gain insight into other national/regional research programmes. This will help managers to follow best practice in terms of implementing international funding calls and harmonise research and policy agendas across nations. The objectives of ERA-GAS will directly address the scope of the Work Programme by incentivising participating countries to commit resources towards the development of a sustainable, innovative and more GHG efficient bioeconomy in Europe. This transnational effort is urgently required to develop mitigation solutions, refine reporting mechanisms and design policy instruments necessary to tackle this key global environmental challenge.

ERA-NET for Monitoring and Mitigation of Greenhouse Gases from Agri- and Silvi-Culture

M-ERA.NET 2 aims at coordinating the research efforts of the participating EU Member States, Associated States and Regions as well as of selected global partners in materials research and innovation, including materials for low carbon energy technologies and related production technologies. A large network of 43 national and regional funding organisations from 23 EU Members States and Associated States and 5 countries outside Europe will implement joint calls to fund excellent innovative transnational RTD cooperation, including one call for proposals with EU co-funding and additional non-cofunded calls.  Continuing the activities started under the predecessor project M-ERA.NET (2/2012-1/2016), the M-ERA.NET 2 consortium will support relevant thematic areas, such as -for example- surfaces, coatings, composites, additive manufacturing or computational materials engineering. Research on materials enabling low carbon energy technologies will be particularly highlighted as a main target of the cofunded call (Call 2016) with a view to implementing relevant parts of the Materials Roadmap Enabling Low Carbon Energy Technologies (SEC(2011)1609), and relevant objectives of the SET-Plan (COM (2009)519). The appropriate scope of the cofunded call and the additional joint calls will be defined in cooperation with relevant stakeholders including national and regional RTD communities, the EC and the EMIRI (Energy Materials Industrial Research Initiative) as well as an external Strategic Experts Group. M-ERA.NET 2 will support the whole innovation chain, clarifying for each topic the appropriate Technology Readiness Levels (TRLs) to be addressed through the transnational RTD projects. The consortium will be aware of the TRLs which are covered by the EC through Horizon 2020 topics as well as by other schemes. Gaps will be identified and M-ERA.NET 2 will aim at offering a complementary support scheme.

ERA-NET for materials research and innovation

European Research Area on Sustainable Animal Production Systems

This proposal seeks funding under the Horizon 2020 Work Programme 2014-2015 to establish an ERA-NET for joint European research coordination on Sustainable Animal Production (SusAn). The scope for this ERA-NET has been developed under the SCAR Collaborative Working Group on Sustainable Animal Production (CWG-SAP).  Funding organisations from 22 European countries initially seek to support one co-funded call followed by other joint activities including the development of a Common Strategic Research and Innovation Agenda on Sustainable Animal Production.  The animal production sector forms an important part of Europe’s (agricultural) economy and plays an essential role in the provision of Europe`s citizens with high quality animal products. Like other agriculture sectors, animal production faces many challenges from projected increases in global demand for food, climate change, competition for natural resources and economic volatility. The European animal production landscape is very complex, consisting of different species farmed within a wide range of different extensive, semi-intensive and intensive production systems using multiple resources to produce a diverse range of animal products and other services. Partners in this ERA-NET believe, however, that these challenges and complexities can be effectively addressed through joint European research within a framework which supports the three pillars of sustainability - economy, environment and society - and targets opportunities for innovative research spanning all areas of animal production such as health and welfare, feeding and nutrition, reproduction, breeding and genetics, housing, nutrient management and economics. Partners in ERA-NET SusAn endorse scientific excellence and recommend an integrated, interdisciplinary, cross-cutting and multi-actor approach to research and knowledge exchange which reflects the complexity of the research requirements for sustainable European animal production.

Accellerating CCS technologies as a new low-carbon energy vector

This ERA-NET Cofund action is a transnational collaboration on CO2 Capture and Storage (CCS) technology. CCS is regarded as one of the main routes for Europe to mitigate climate change. Our initiative "Accelerating CCS technology as a new low-carbon energy vector" (ACT) targets mainly the energy sector, but will also have benefits for energy intensive industries. The vision of ACT is to ensure that the energy sector makes a better contribution to climate protection by developing a collection of different CCS technologies ready for commercialisation. The consortium consists of 10 partners from 9 countries highly engaged to further development of CCS. The partner contribution for the first call is Euros 28.8 million. The consortium has received Letter of Support (LOS) from several important stakeholders in the CCS area in Europe.  The main objective of ACT is to facilitate the emergence of CCS by significant transnational joint calls that will stimulate close cooperation between researchers and industry in order to accelerate the deployment of CCS. During these calls the consortium will address the most relevant RD&D gaps in the CCS chain. ACT will bring researchers and CCS stakeholders from a number of countries closer together in a joint effort that will generate momentum towards deployment of CCS technology in Europa.  ACT will fund transnational R&D and innovation projects, facilitate meeting places for knowledge sharing, ensure synergies with pilots and demonstration projects, and invite to discussions with stakeholders in the CCS field. ACT will also ensure dissemination of results from ACT funded projects as part of an extensive outreach program targeting the research community, policymakers and the public in general. The result will be new knowledge which in turn will close gaps and accelerate CCS deployment.  ACT has seven work packages, of which five are directly related to the first call and the last two are dedicated to additional activities.

The STI cooperation between the EU and South Africa as originally framed by the South Africa-EU Scientific and Technological Cooperation Agreement and as constantly steered by the JSTCC requires a support mechanism which can translate and facilitate policy decisions, and provide intelligence and information services to various actors and stakeholders. In previous years the ESASTAP project series (ESASTAP, ESASTAP-2 and ESASTAP+) has successfully provided this support to the bilateral dialogue. The proposed ESASTAP 2020 project is a coordination and support action that aims at advancing further the EU-SA bilateral STI cooperation, building on the work and results of three preceding actions and responding to the needs and recommendations at the policy dialogue level, in particular to the mandate of the JSTCC and to the adopted Roadmap for cooperation between South Africa and the European Union. The project aims to provide efficient services on three levels (priority areas):  a.	R&I Cooperation in areas of common interests (Horizon 2020 and others).   b.	Policy Dialogue between EU and SA and by increasing the knowledge of the EU’s external environment.  c.	Provision of a Cooperation platform and tools to alleviate obstacles.  These priority areas translate into four major objectives through which the project is aiming to address the specific challenges of the call. 

Strengthening Technology, Research and Innovation Cooperation between Europe and South Africa 2020

CSA Oceans 2 is a 36 month project with the general aim to facilitate and support the implementation of the Strategic Research and Innovation Agenda (SRIA) of JPI Oceans. CSA Oceans 2 will build further on the outcomes of the FP7 CSA Oceans project. To achieve the objective above the project has been organised in five work packages: - WP1 will allow to link closely the project with the JPI Oceans structures namely the Management Board, the Executive Committee, Strategic Advisory Board and the JPI Oceans Secretariat and involve them in the CSA activities - WP2 will deal with the implementation of joint transnational activities and will facilitate the organisation of the activities, it will guide the member countries in identifying and selecting the best fit for purpose (new) tools and provide a framework for evaluating, assessing and monitoring of the actions - WP3 aims at maintaining and further developing the relationships between JPI Oceans with different relevant actors (research funding organisations (RFOs), Ministries, research performing organisations (RPOs), industry and partners outside of the EU) in the field of marine and maritime sciences in supporting the implementation of JPI Oceans agreed actions - WP4 will support the implementation of the SRIA through thematic foresight mechanisms and will design a process for JPI Oceans to update its SRIA, Implementation Plan and Operational plan. - WP5 will deliver the necessary tools for the information management as well as outreach and dissemination of CSA Oceans 2 project and JPI Oceans' activities. The CSA Oceans 2 project will be performed by a consortium of a mix of funding, coordinating and research performing organisations. All are members of the JPI Oceans Management Board or have a close connection to their national Management Board member.  

Coordination action in support of the implementation of the Joint Programming Initiative on 'Healthy and Productive Seas and Oceans'

The ERA-NET NEURON Cofund will coordinate and align European and international research funding programmes in the area of brain-related diseases and disorders of the nervous system. Key activity is the implementation of an EC co-funded joint transnational call for research proposals. The mission of NEURON is based on the fact that disorders of the brain are the major cause for impaired quality of life, and they are a heavy burden not only for patients, their families and carers, but also a socioeconomic problem for society. By improving collaboration and by implementing a variety of additional activities (such as further joint transnational calls and support of early-career scientists) NEURON Cofund will decrease fragmentation of research programmes and improve the funding situation for neuroscience researchers thereby strengthening the search for novel therapeutic approaches to fight brain disease;  NEURON Cofund will also develop and provide concrete plans for (i) expanding data sharing, (ii) promoting common data elements for the establishment of patient registries, and (iii) involving stakeholders and relevant existing initiatives such as patient organizations. The aforementioned challenges will be addressed in a network of 22 funding organizations across 14 European Member and Associated States and Third countries. 

ERA NET NEURON in the area of brain-related diseases and disorders of the nervous system

DemoWind 2 ERA-NET Cofund action - delivering cost reduction in offshore wind

DemoWind 2 proposes to bring together a number of national and transnational organisations with an interest in accelerating cost reduction in offshore wind. It follows on from the first DemoWind initiative that launched in 2014 and, like its predecessor, is focussed on enabling industry, through partnership, to push technologies through TRLs 5-6 to 6-7 in transnationally funded projects.  We aim to connect existing and new European offshore wind demonstration opportunities, exchange knowledge and facilitate the acceleration of cost reducing innovative technologies to commercialisation. This action will contribute to European cost reduction targets for offshore wind, economic development of the European offshore wind sector and help to maintain the EU’s internationally leading position in offshore wind.  Reducing technology cost is essential to increasing the deployment of offshore wind, making a significant contribution to the EU’s climate change targets, replacing aging fossil burning power plants with affordable energy.   The main objectives of the DemoWind  2 project are split into two parts: •Part A is dedicated to activities related to the main co-funded Call (Work Packages 1-5) •Part B is dedicated to additional activities (Work Packages 6-7), which will be aimed at widening the dissemination of technologies supported by DemoWind 2 and at identifying and taking forward further opportunities for the DemoWind 2 partners and others to fund further RD&D activities targeting cost reduction in offshore wind without Commission funding. Initially, these additional activities will involve DemoWind 2 strengthening links with existing OSW industry groups looking at innovation and cost reduction, specifically  the OWA Europe programme.

Water Works 2016-2020 in Support of the Water JPI (WaterWorks2015) - Sustainable water use in agriculture, to increase water use efficiency and reduce soil and water pollution

The WaterWorks2015 proposal responds to the Horizon 2020 (H2020) Societal Challenge 5 2015 Call topic Water-3 [2015]: Stepping up EU research and innovation cooperation in the water area. WaterWorks2015 aims at pooling resources from the 32 participating research programme owners / managers of 23 countries to implement a joint call for proposals, with EU co-funding in the area of sustainable water use in agriculture and forestry. It's a collaboration between the Joint Programming Initiatives (JPIs), Water JPI “Water Challenges for a Changing World” and FACCE JPI “Agriculture, Food Security and Climate Change”. Achieving a “sustainable water use in agriculture, to increase water use efficiency and reduce soil and water pollution” is at the intersection of the two JPIs, contributing to the implementation of their respective Strategic Research Agendas. WaterWorks2015 includes 9 organisations from associated and third countries in an effort to reinforce international cooperation. Additional Activities will also be carried out to further support the implementation and strategy of the Water JPI. The overall aims include: • Increasing the value of relevant national and EU R&D funding by concerted and joint planning, implementation and evaluation of national research programmes;  • Pooling financial resources from participating states towards the definition and implementation of a Co-funded transnational and multi-disciplinary Call for research and innovation proposals. The aim of the Call will be to support the implementation of initiatives and environmental policies, in particular those related to water and agriculture & forestry, as a way to increase water use efficiency and to reduce soil and water pollution; • Overcoming the fragmentation of European water and agriculture/forestry-related research and innovation activities;  • Supporting the implementation and the development of the two Joint Programming Initiatives, seeking synergies in overlapping research issues.

European Research Area for Climate Services

Within the European Research Area (ERA), the ERA4CS Consortium is aiming to boost, research for Climate Services (CS), including climate adaptation, mitigation and disaster risk management, allowing regions, cities and key economic sectors to develop opportunities and strengthen Europe’s leadership. CS are seen by this consortium as driven by user demands to provide knowledge to face impacts of climate variability and change, as well as guidance both to researchers and decisionmakers in policy and business.  ERA4CS will focus on the development of a “climate information translation” layer bridging “user communities” and “climate system sciences”. It implies the development of tools, methods, standards and quality control for reliable, qualified and tailored information required by the various field actors for smart decisions. ERA4CS will boost the JPI Climate initiative by mobilizing more countries, within EU Member States and Associated Countries, by involving both the research performing organizations (RPOs) and the research funding organizations (RFOs), the distinct national climate services and the various disciplines of academia, including Social Sciences and Humanities. ERA4CS will launch a joint transnational co-funded call, with over 16 countries and up to 75M€, with two complementary topics: (i) a “cash” topic, supported by 12 RFOs, on co-development for user needs and action-oriented projects; (ii) an “in-kind” topic, supported by 28 RPOs, on institutional integration of the research components of national CS.  Finally, ERA4CS additional activities will initiate a strong partnership between JPI Climate and others key European and international initiatives (as Copernicus, KIC-Climate, JPIs, WMO/GFCS, Future Earth, Belmont Forum…) in order to work towards a common vision and a multiyear implementation strategy, including better co-alignment of national programs and activities up to 2020 and beyond.

Antibiotic resistance is a global problem. It is considered by the World Health Organization as one of the three greatest threats to human health for the next decades. ’Enhanced coordination across national boundaries is needed to accelerate the efforts to tackle this grand challenge. Such synergies have been created among 19 countries in Europe and beyond through the EU JPI on Antimicrobial Resistance (JPIAMR). JPIAMR has developed a Strategic Research Agenda (SRA) which defines the strategic and scientific priorities benefiting from co-ordination and co-operation at the European level and mobilised national funds for two joint transnational calls (JTC) 2014 and 2015 based on this. In the ERA-NET Cofund JPI-EC-AMR, an additional € 23 million of national funds will be combined with a highly incentivising EC top-up fund to support a new transnational research programme. The aim of this programme is to unravel the complex dynamics of selection and transmission of antimicrobial resistance (AMR) according to the One Health concept. A multidisciplinary approach is necessary to identify and characterise the determinants that contribute to the spread of resistance at genetic, bacterial, animal, human, societal, and environmental levels, in order to provide scientific knowledge to design and evaluate cost-effective strategies that can decrease transmission of AMR in society. JPI-EC-AMR will launch additional JTCs without EC co-funding under the framework of the SRA. and perform additional joint actions in close collaboration with JPIAMR actions. JPI-EC-AMR will provide a better, quantitative understanding of drug-resistant bacteria in animals, foods, and the environment and to what extent they contribute to the burden of antibiotic-resistant infections in humans. Research in this area is crucial in order to provide the robust scientific evidence needed to make informed decisions regarding interventions and policy measures in hospital, community, and agricultural settings.  

ERA-NET for establishing synergies between the Joint Programming Initiative on Antimicrobial Resistance Research and Horizon 2020

Cardiovascular diseases (CVD) are the largest cause of death in the EU and account for around 2 million deaths per year. Overall, CVD are estimated to cause the economy of the EU costs of almost 196 billion Euros a year. Furthermore, they are one of the leading causes of long term sickness, chronic diseases and loss to the labour market. Therefore, CVD are a major health problem in Europe. Despite the overall burden of CVD on European citizens and national health systems, translational cardiovascular research is fragmented and mainly occurs at national levels. However, the present and future challenges in cardiovascular research can only be met by an effective cooperation at transnational level. Therefore, the proposed European Research Area Network on cardiovascular diseases (ERA-CVD) aims to coordinate national and regional programmes for translational research in the area CVD by implementing one Joint Transnational Call (JTC2016) with EU Co-funding followed by further non-co-funded JTC (2017-2019). Although this consortium will be newly established, a collaboration and alignment of national programmes and activities has already been achieved during the preparation of the ERA-Net Co-fund proposal. This process is supported by CardioScape an EU-funded survey of the European cardiovascular research landscape coordinated by the European Society of Cardiology (ESC). The current ERA-CVD proposal will extend and strengthen the transnational cooperation of the current 23 ministries/institutions/foundations from 18 European, associated and third countries. Furthermore, ERA-CVD plans to cooperate with the ESC and the European Heart Network (EHN). Moreover, the collaboration with European Research Infrastructures, e.g. the ESFRI-initiatives is intended in order to set up an efficient European framework for innovative transnational research on CVD. Also the extension of the consortium and international collaborations are intended.

ERA-NET on cardiovascular diseases to implement joint transnational research projects and set up international cooperations

The EURAXESS TOP III consortium includes partners from almost all EURAXESS countries (either as beneficiaries or associated partners, from altogether 39 countries), in order to ensure the widest possible coverage as well as increased impact.  The project has been divided into eight work packages. Two WPs are devoted to the development, testing and pilot introduction of new services on career development within the EURAXESS network. The remaining WPs will focus on the environment of researchers including the institutional context, the integration of third country researchers and reaching out to researchers beyond the EU; researchers within and outside academia, most notably industry; the consolidation of the ongoing services portfolio, be it personal or electronic; the further capacity building of the EURAXESS network members and meeting the challenge posed by staff turnover by trainings, twinning and study visits; networking and knowledge exchange with a wide range of other networks; implementation of a consistent quality assurance and monitoring system operating on several levels on the project, and working out a future vision for EURAXESS in light of the policy goals of the EC set for the period up to 2020.  The project will significantly contribute to matching research talents with R&I needs and capacity on a European scale and it will help the circulation of researchers within Europe and among sectors.  As a result of the project, members of the EURAXESS network will have better and broader knowledge and more integrated good practices regarding service provision for researchers. EURAXESS national portals throughout the EURAXESS member countries will offer tailor made information in line with Horizon 2020 objectives on making science careers attractive for researchers, especially young researchers.  

Making European research careers more attractive by developing new services and enhancing the current services of the EURAXESS network – EURAXESS TOPIII

CIMULACT has as a main objective to add to the relevance and accountability of European research and innovation – Horizon 2020 as well as national - by engaging citizens and stakeholders in co-creation of research agendas based on real and validated societal visions, needs and demands. The project will expand the outlook and debate on STI issues, increase scientific literacy in a broad sense, which includes the understanding of the societal role of Science, Technology and innovation (STI), and create shared understanding between scientific stakeholders, policy-makers and citizens. This multi-actor approach will embrace EU28 plus Norway and Switzerland.  The CIMULTACT builds on the principle/conviction that the collective intelligence of society gives Europe a competitive advantage, which may be activated to strengthen the relevance of the European science and technology system. By establishing genuine dialogue between citizens, stakeholders, scientists, and policymakers visions and scenarios for the desirable futures will be developed and debated, and transformed into recommendations and suggestions for research and innovation policies and topics.   In short, CIMULACT will  Create vision and scenarios that connect societal needs with future expected advances in Science and their impact on technology, society, environment etc. in connection to the grand challenges  Provide concrete input to Horizon 2020 through recommendations and policy options for R&I and simulated calls for the Horizon2020 Work Programmes.  Engage citizens and stakeholders in a highly participatory debate/consultation/process on scenarios for desirable sustainable futures and research  Build capacities in citizen and multi-actor engagement in R&I through development, experimentation, training and assessment of methods for engagement  Facilitate dialogue and shared understanding between policymakers, citizens, and stakeholders  Reveal  the relative merits of the citizen focussed consultations

CITIZEN AND MULTI-ACTOR CONSULTATION ON HORIZON2020

Environmental Research Infrastructures Providing Shared Solutions for Science and Society

ENVRIPLUS is a cluster of research infrastructures (RIs) for Environmental and Earth System sciences, built around ESFRI roadmap and associating leading e-infrastructures and Integrating Activities together with technical specialist partners. ENVRIPLUS is driven by 3 overarching goals: 1) favoring cross-fertilization between infrastructures, 2) implementing innovative concepts and devices across RIs, and 3) facilitating research and innovation in the field of environment to an increasing number of users outside the RIs. ENVRIPLUS organizes its activities along a main strategic plan where sharing multi-disciplinary expertise will be most effective. It aims to improve Earth observation monitoring systems and strategies, including actions towards harmonization and innovation, to generate common solutions to many shared information technology and data related challenges, to harmonize policies for access and provide strategies for knowledge transfer amongst RIs. ENVRIPLUS develops guidelines to enhance trans-disciplinary use of data and data-products supported by applied use-cases involving RIs from different domains. ENVRIPLUS coordinates actions to improve communication and cooperation, addressing Environmental RIs at all levels, from management to end-users, implementing RI-staff exchange programs, generating material for RI personnel, and proposing common strategic developments and actions for enhancing services to users and evaluating the socio-economic impacts.  ENVRIPLUS is expected to facilitate structuration and improve quality of services offered both within single RIs and at pan-RI level. It promotes efficient and multi-disciplinary research offering new opportunities to users, new tools to RI managers and new communication strategies for environmental RI communities. The produced solutions, services and other project results are made available to all environmental RI initiatives, thus contributing to the development of a consistent European RI ecosystem.

The rapid changes occurring in the Polar Regions are significantly influencing global climate with consequences for global society. European polar research has contributed critical knowledge to identifying the processes behind these rapid changes but, in contrast to lower latitudes, datasets from the Polar Regions are still insufficient to fully understand and more effectively predict the effects of change on our climate and society. This situation can only be improved by a more holistic integrated scientific approach, a higher degree of coordination of polar research and closer cooperation with all relevant actors on an international level as requested in the Horizon 2020 work programme.  The objectives of EU-PolarNet are to establish an ongoing dialogue between policymakers, business and industry leaders, local communities and scientists to increase mutual understanding and identify new ways of working that will deliver economic and societal benefits. The results of this dialogue will be brought together in a plan for an Integrated European Research Programme that will be co-designed with all relevant stakeholders and coordinated with the activities of many other polar research nations beyond Europe, including Canada and the United States, with which consortium partners already have productive links. This consortium brings together well-established, world-class, multi-disciplinary research institutions whose science programmes are internationally recognised for excellence. Alongside these scientific capabilities, the national programmes represented in this proposal possess a unique array of infrastructure and operational expertise to support science in both Polar Regions. The consortium is uniquely well positioned to significantly enhance Europe’s capabilities to undertake state of the art science and cost-efficiently operate infrastructure in the hostile polar environments. 

Connecting Science with Society

SUstainable and Resilient agriculture for food and non-food systems

The objective of FACCE SURPLUS is to strengthen the European Research Area in support of different integrated food and non-food biomass production and transformation systems, especially by organising, implementing and cofunding with the EU a joint call for transnational research projects on the topic of sustainable and resilient agriculture. As this topic falls within the scope of the Strategic Research Agenda (SRA) of the Joint Programming Initiative on Agriculture, Food Security and Climate Change (FACCE–JPI), this ERA-NET Cofund will contribute substantially to the delivery of the FACCE–JPI SRA. It will thereby also contribute to the overall EU objective of building the European Research Area through enhanced cooperation, coordination and alignment of national research programmes.  The action FACCE SURPLUS also aims at implementing other joint activities such as organizing workshops, scientific events, clustering of research platforms and infrastructures in the field of food and non-food biomass production and transformation systems, and also additional joint calls without EU cofunding. Launching such joint calls on a regular basis would pave the way to the long term objective of FACCE SURPLUS to establish a self-sustaining joint programme for FACCE-JPI. This will include establishing links with ongoing FACCE-JPI actions as well as related EU and international initiatives. FACCE SURPLUS will also support innovation and value creation from biomass in a sustainable way. The ERA-NET Cofund instrument is appropriate for FACCE-JPI, since it provides additional incentive to participating countries to engage financially on the field of sustainable and resilient agriculture, but also includes the flexibility to implement further activities to contribute to the establishment of a renewable bioeconomy in the ERA.

Consolidating the European Research Area on biodiversity and ecosystem services

The loss of biodiversity and degradation of ecosystems jeopardize the sustainable provision of ecosystem services and are major scientific and societal challenges. Addressing this challenge and providing scientific support to stakeholders and policy makers requires a coherent interdisciplinary research framework, with coordinated strategies and programmes at the national, regional and international levels, which are the relevant scales for many biodiversity issues.  By networking 32 funding agencies from 18 countries, BiodivERsA3 aims to strengthen the ERA on biodiversity. Building on the previous experiences of the projects BiodivERsA1&2 and NetBiome, BiodivERsA3 will promote and support coordinated pan-European research on biodiversity and ecosystem services. It will strengthen research and research programmes coordination with the ultimate aim to provide policy makers and other stakeholders with adequate knowledge, tools and practical solutions to address biodiversity and ecosystem degradation.   The objectives are to:  - Enhance the capacity of the network to coordinate research programmes on biodiversity and ecosystem services more completely in Europe (including overseas territories) and to increase the international dimension of BiodivERsA activities - Develop a strategic, multi-annual vision of the network’s priorities, based on ambitious mapping and foresight activities developed in collaboration with key initiatives in the field - Design and implement a co-funded call and other joint calls to better integrate research on biodiversity and ecosystem services across Europe - Develop a range of other joint activities, in particular alignment of national research programmes for biodiversity and ecosystem services, and activities for promoting mobility and equal opportunities for researchers and reinforcing data sharing - Promote effective science-policy and science-society (including science-business) dialogue during the whole research process

Water Works 2014-2019 in Support of the Water JPI

Water is a critical resource for the European society. Beside its main life function, freshwater also provides many other functions essential to our economy. Water challenges cannot be successfully tackled through the isolated effort of individual national research and innovation programmes. This ERA-NET cofund proposal is submitted in the name of the Joint Programming Initiative “Water Challenges for a Changing World”, and aims at contributing to tackle European water challenges through the development of transnational and trans-disciplinary research and innovation actions. WaterWorks2014 addresses the specific challenge of integrating the efforts and Strategic Agendas of many European Water Research and Innovation funding organizations. This ERA-NET cofund will implement a Call for proposals on “research and innovation developing technological solutions and services to support the implementation of EU water policy, in particular for water distribution and measurement, waste water treatment and reuse, desalination, floods and droughts etc.” This Call for proposals will be funded by 18 organizations from 16 countries, and will have a total budget of 15.2 million Euro. This total budget includes a cofund from the European Commission amounting to 5.0 million Euro. WaterWorks2014 will also perform additional activities contributing to Water JPI Strategy and Implementation. Activities contributing to strategy include the development of new versions of the Water JPI Strategic Agenda and the Implementation Plan. Activities contributing to implementation include sharing good practices on Water research and innovation funding and management, exploratory workshops, alignment of on-going projects and the monitoring and final evaluation of Calls without cofunding. WaterWorks2014 will benefit researchers, policy-makers, water authorities, utility operators, industry, farmers, and citizens by developing new solutions to water challenges.

ERA-Net Smart Grids Plus: support deep knowledge sharing between regional and European Smart Grids initiatives

"From local trials to a European knowledge community".  The challenges of modernising the electricity grids in Europe lies in enabling an increased flexibility of the European power system, efficiently providing increased transfer capacity and enabling an active participation of users and new market actors (by providing the information, services, market architectures and privacy guarantees). To address these challenges, innovation is needed in system integration, interoperable technologies, services, tools, co-ordination schemes, business processes, market architectures and regulatory regimes to plan, build, monitor, control and safely operate end-to-end networks in an open, competitive, decarbonised, sustainable and climate-change resilient market, under normal and emergency conditions.  The major challenge is now to overcome the fragmentation of knowledge and accelerate knowledge exchange between the already existing demonstration projects and R&D initiatives with the goal to enable them to develop European wide interoperable solutions, according to a common reference architecture. With this, critical masses shall be reached in the development of a European market for smart grids technology providers and smart grids service providers.  This initiative does not intend to find the final specifications for smart grids, but to organise the learning down to regional Smart Grids stakeholders, beyond the demonstration phase towards implementation.  The overall goal of the “ERA-Net Smart Grids Plus” is to support deep knowledge sharing between regional and European Smart Grids initiatives by financing 15-20 transnational projects on applied research, piloting and demonstration in the field of Smart Grids, taking a next step in Smart Grids development building on the knowledge base, R&D initiatives as well as research and demonstration facilities already in place at regional, national and European level. It will coordinate during 2015-19 national and regional RDD budgets of more than 30 M€.

MCA-3.01 Marie Curie Actions

Rheumatoid Arthritis and Periodontal Inflammatory Disease (RAPID)

Tildelt: kr 3,1 mill.

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MCA-3.01 Marie Curie Actions

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